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Towards a better preclinical cancer model – human immune aging in humanized mice

BACKGROUND: Preclinical models are often used for cancer studies and evaluation of novel therapeutics. The relevance of these models has vastly improved with mice bearing a human immune system, especially in the context of immunotherapy. Nonetheless, cancer is an age-related disease, and studies oft...

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Detalles Bibliográficos
Autores principales: Tan, Joel H. L., Hwang, You Yi, Chin, Hui Xian, Liu, Min, Tan, Sue Yee, Chen, Qingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10523735/
https://www.ncbi.nlm.nih.gov/pubmed/37752597
http://dx.doi.org/10.1186/s12979-023-00374-4