Cargando…

Cellular and Molecular Mechanisms of the Tumor Stroma in Colorectal Cancer: Insights into Disease Progression and Therapeutic Targets

Colorectal cancer (CRC) is a major health burden worldwide and is the third most common type of cancer. The early detection and diagnosis of CRC is critical to improve patient outcomes. This review explores the intricate interplay between the tumor microenvironment, stromal interactions, and the pro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shakhpazyan, Nikolay, Mikhaleva, Liudmila, Bedzhanyan, Arkady, Gioeva, Zarina, Sadykhov, Nikolay, Mikhalev, Alexander, Atiakshin, Dmitri, Buchwalow, Igor, Tiemann, Markus, Orekhov, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525158/ https://www.ncbi.nlm.nih.gov/pubmed/37760801 http://dx.doi.org/10.3390/biomedicines11092361

Ejemplares similares

Long Non-Coding RNAs in Colorectal Cancer: Navigating the Intersections of Immunity, Intercellular Communication, and Therapeutic Potential
por: Shakhpazyan, Nikolay K., et al.
Publicado: (2023)

Signaling Pathways in the Pathogenesis of Barrett’s Esophagus and Esophageal Adenocarcinoma
por: Maslenkina, Ksenia, et al.
Publicado: (2023)

Immunophenotyping of the PD-L1-positive cells in angioimmunoblastic T cell lymphoma and Hodgkin disease
por: Tiemann, Markus, et al.
Publicado: (2020)

Expression of CD38 in Mast Cells: Cytological and Histotopographic Features
por: Atiakshin, Dmitri, et al.
Publicado: (2021)

Identification of CTLA-4-Positive Cells in the Human Tonsil
por: Tiemann, Markus, et al.
Publicado: (2021)

Protease profile of normal and neoplastic mast cells in the human bone marrow with special emphasis on systemic mastocytosis
por: Atiakshin, Dmitri, et al.
Publicado: (2021)

Protease Profile of Tumor-Associated Mast Cells in Melanoma
por: Atiakshin, Dmitri, et al.
Publicado: (2022)

Carboxypeptidase A3—A Key Component of the Protease Phenotype of Mast Cells
por: Atiakshin, Dmitri, et al.
Publicado: (2022)

Mast Cell Tryptase and Carboxypeptidase A3 in the Formation of Ovarian Endometrioid Cysts
por: Atiakshin, Dmitri, et al.
Publicado: (2023)

Chloroacetate esterase reaction combined with immunohistochemical characterization of the specific tissue microenvironment of mast cells
por: Atiakshin, Dmitri, et al.
Publicado: (2023)

Novel Models of Crohn’s Disease Pathogenesis Associated with the Occurrence of Mitochondrial Dysfunction in Intestinal Cells
por: Blagov, Alexander, et al.
Publicado: (2022)

The Remodeling of Dermal Collagen Fibrous Structures in Mice under Zero Gravity: The Role of Mast Cells
por: Shishkina, Viktoriya, et al.
Publicado: (2023)

Phenotype Diversity of Macrophages in Osteoarthritis: Implications for Development of Macrophage Modulating Therapies
por: Mushenkova, Nataliya V., et al.
Publicado: (2022)

Mast Cells in Regeneration of the Skin in Burn Wound with Special Emphasis on Molecular Hydrogen Effect
por: Atiakshin, Dmitri, et al.
Publicado: (2023)

Mast Cells as a Potential Target of Molecular Hydrogen in Regulating the Local Tissue Microenvironment
por: Atiakshin, Dmitri, et al.
Publicado: (2023)

The Role of Altered Mitochondrial Metabolism in Thyroid Cancer Development and Mitochondria-Targeted Thyroid Cancer Treatment
por: Dabravolski, Siarhei A., et al.
Publicado: (2021)

Smooth Muscle Actin as a Criterion for Gravisensitivity of Stomach and Jejunum in Laboratory Rodents
por: Samoilenko, Tatyana, et al.
Publicado: (2023)

Pathomorphological Features of the Novel Coronavirus Disease in Patients with Systemic Amyloidosis
por: Mikhaleva, Liudmila, et al.
Publicado: (2023)

Space-Flight- and Microgravity-Dependent Alteration of Mast Cell Population and Protease Expression in Digestive Organs of Mongolian Gerbils
por: Atiakshin, Dmitrii, et al.
Publicado: (2023)

Mitochondrial Implications in Cardiovascular Aging and Diseases: The Specific Role of Mitochondrial Dynamics and Shifts
por: Poznyak, Anastasia V., et al.
Publicado: (2022)

The Role of KLF2 in the Regulation of Atherosclerosis Development and Potential Use of KLF2-Targeted Therapy
por: Dabravolski, Siarhei A., et al.
Publicado: (2022)

Non-specific binding of antibodies in immunohistochemistry: fallacies and facts
por: Buchwalow, Igor, et al.
Publicado: (2011)

Functional Phenotypes of Intraplaque Macrophages and Their Distinct Roles in Atherosclerosis Development and Atheroinflammation
por: Mushenkova, Nataliya V., et al.
Publicado: (2022)

Effects of Metabolic Disorders in Immune Cells and Synoviocytes on the Development of Rheumatoid Arthritis
por: Blagov, Alexander V., et al.
Publicado: (2022)

New Insight into the Role of Nitric Oxide Pathways in Pancreas
por: Buchwalow, Igor, et al.
Publicado: (2018)

Role of Impaired Mitochondrial Dynamics Processes in the Pathogenesis of Alzheimer’s Disease
por: Blagov, Alexander V., et al.
Publicado: (2022)

The Role of Mitochondrial Abnormalities in Diabetic Cardiomyopathy
por: Dabravolski, Siarhei A., et al.
Publicado: (2022)

Interplay between Zn(2+) Homeostasis and Mitochondrial Functions in Cardiovascular Diseases and Heart Ageing
por: Dabravolski, Siarhei A., et al.
Publicado: (2022)

Aging of Vascular System Is a Complex Process: The Cornerstone Mechanisms
por: Poznyak, Anastasia V., et al.
Publicado: (2022)

Atherosclerosis Specific Features in Chronic Kidney Disease (CKD)
por: Poznyak, Anastasia V., et al.
Publicado: (2022)

The Role of Mitochondrial DNA Mutations in Cardiovascular Diseases
por: Dabravolski, Siarhei A., et al.
Publicado: (2022)

Hypertension as a risk factor for atherosclerosis: Cardiovascular risk assessment
por: Poznyak, Anastasia V., et al.
Publicado: (2022)

Cellular organization and histogenesis of adenosquamous carcinoma of the pancreas: evidence supporting the squamous metaplasia concept
por: Boecker, Werner, et al.
Publicado: (2020)

Hedgehog Signaling in Colorectal Cancer: All in the Stroma?
por: Geyer, Natalie, et al.
Publicado: (2021)

Modulating mTOR Signaling as a Promising Therapeutic Strategy for Atherosclerosis
por: Poznyak, Anastasia V., et al.
Publicado: (2022)

Glycation of LDL: AGEs, impact on lipoprotein function, and involvement in atherosclerosis
por: Poznyak, Anastasia V., et al.
Publicado: (2023)

Cellular Mechanisms of Human Atherogenesis: Focus on Chronification of Inflammation and Mitochondrial Mutations
por: Markin, Alexander M., et al.
Publicado: (2020)

Novel 3D µtissues Mimicking the Fibrotic Stroma in Pancreatic Cancer to Study Cellular Interactions and Stroma-Modulating Therapeutics
por: Pednekar, Kunal P., et al.
Publicado: (2021)

Can the stroma provide the clue to the cellular basis for mammographic density?
por: Warren, Ruth, et al.
Publicado: (2003)

Macrophage–stroma interactions in fibrosis: biochemical, biophysical, and cellular perspectives
por: Vasse, Gwenda F, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_i1nrhhj88mqsk5dgshi5v4hrra