Repositioning of HMG-CoA Reductase Inhibitors as Adjuvants in the Modulation of Efflux Pump-Mediated Bacterial and Tumor Resistance

Efflux pump (EP)-mediated multidrug resistance (MDR) seems ubiquitous in bacterial infections and neoplastic diseases. The diversity and lack of specificity of these efflux mechanisms raise a great obstacle in developing drugs that modulate efflux pumps. Since developing novel chemotherapeutic drugs...

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Detalles Bibliográficos
Autores principales: Schelz, Zsuzsanna, Muddather, Hiba F., Zupkó, István
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525194/
https://www.ncbi.nlm.nih.gov/pubmed/37760764
http://dx.doi.org/10.3390/antibiotics12091468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525194/
https://www.ncbi.nlm.nih.gov/pubmed/37760764
http://dx.doi.org/10.3390/antibiotics12091468

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