Cargando…

Piperlongumine Induces Apoptosis and Cytoprotective Autophagy via the MAPK Signaling Pathway in Human Oral Cancer Cells

Oral cancer is a malignant tumor that primarily affects areas such as the lips, tongue, buccal mucosa, salivary gland, and gingiva and has a very high malignancy. Piperlongumine (PL), isolated from long pepper (Piper longum L.), is a natural alkaloid with pharmacological effects, such as anti-inflam...

Descripción completa

Detalles Bibliográficos
Autores principales:	Choi, Eun-Young, Han, Eun-Ji, Jeon, Su-Ji, Lee, Sang-Woo, Moon, Jun-Mo, Jung, Soo-Hyun, Jung, Ji-Youn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525218/ https://www.ncbi.nlm.nih.gov/pubmed/37760883 http://dx.doi.org/10.3390/biomedicines11092442

Ejemplares similares

Piperlongumine induces apoptosis via the MAPK pathway and ERK-mediated autophagy in human melanoma cells
por: Jeon, Su-Ji, et al.
Publicado: (2023)

Piperine Induces Apoptosis and Autophagy in HSC-3 Human Oral Cancer Cells by Regulating PI3K Signaling Pathway
por: Han, Eun-Ji, et al.
Publicado: (2023)

Chrysin Induces Apoptosis via the MAPK Pathway and Regulates ERK/mTOR-Mediated Autophagy in MC-3 Cells
por: Jung, Gi-Hwan, et al.
Publicado: (2022)

Myricetin induces apoptosis through the MAPK pathway and regulates JNK-mediated autophagy in SK-BR-3 cells
por: Han, So-Hee, et al.
Publicado: (2022)

Chrysin Induces Apoptosis and Autophagy in Human Melanoma Cells via the mTOR/S6K Pathway
por: Lee, Jae-Han, et al.
Publicado: (2022)

Shikonin inhibits proliferation of melanoma cells by MAPK pathway-mediated induction of apoptosis
por: Lee, Jae Han, et al.
Publicado: (2021)

Silymarin inhibits proliferation of human breast cancer cells via regulation of the MAPK signaling pathway and induction of apoptosis
por: Kim, Sung-Hyun, et al.
Publicado: (2021)

Piperlongumine induces autophagy by targeting p38 signaling
por: Wang, Y, et al.
Publicado: (2013)

Tat-Thioredoxin-like protein 1 attenuates ischemic brain injury by regulation of MAPKs and apoptosis signaling
por: Cha, Hyun Ju, et al.
Publicado: (2023)

Fucoxanthin, the constituent of Laminaria japonica, triggers AMPK-mediated cytoprotection and autophagy in hepatocytes under oxidative stress
por: Jang, Eun Jeong, et al.
Publicado: (2018)

Crosstalk between Fisetin-induced Apoptosis and Autophagy in Human Oral Squamous Cell Carcinoma
por: Park, Bong-Soo, et al.
Publicado: (2019)

Subacute Oral Toxicity Evaluation of Expanded-Polystyrene-Fed Tenebrio molitor Larvae (Yellow Mealworm) Powder in Sprague-Dawley Rats
por: Choi, Eun-Young, et al.
Publicado: (2022)

Propofol protects against oxidative-stress-induced COS-7 cell apoptosis by inducing autophagy
por: Yoon, Ji-Young, et al.
Publicado: (2017)

Silymarin induces inhibition of growth and apoptosis through modulation of the MAPK signaling pathway in AGS human gastric cancer cells
por: Kim, Sung-Hyun, et al.
Publicado: (2019)

Apigenin induces apoptosis by regulating Akt and MAPK pathways in human melanoma cell A375SM
por: Woo, Joong-Seok, et al.
Publicado: (2020)

Myricetin induces apoptosis and autophagy in human gastric cancer cells through inhibition of the PI3K/Akt/mTOR pathway
por: Han, So-Hee, et al.
Publicado: (2022)

Cytoprotective roles for autophagy
por: Moreau, Kevin, et al.
Publicado: (2010)

Piperlongumine restores the balance of autophagy and apoptosis by increasing BCL2 phosphorylation in rotenone-induced Parkinson disease models
por: Liu, Jia, et al.
Publicado: (2018)

Preformulation Studies on Piperlongumine
por: Aodah, Alhassan, et al.
Publicado: (2016)

Cytoprotective effect of flavonoid‐induced autophagy on bisphosphonate mediated cell death in osteoblast
por: Kim, Jung‐Han, et al.
Publicado: (2018)

Deoxypodophyllotoxin Induces ROS-Mediated Apoptosis by Modulating the PI3K/AKT and p38 MAPK-Dependent Signaling in Oral Squamous Cell Carcinoma
por: Seo, Ji-Hye, et al.
Publicado: (2022)

Corrigendum to: Deoxypodophyllotoxin Induces ROSMediated Apoptosis by Modulating the PI3K/AKT and p38 MAPK-Dependent Signaling in Oral Squamous Cell Carcinoma
por: Seo, Ji-Hye, et al.
Publicado: (2022)

Piperlongumine selectively kills cancer cells and increases cisplatin antitumor activity in head and neck cancer
por: Roh, Jong-Lyel, et al.
Publicado: (2014)

Remifentanil induces autophagy and prevents hydrogen peroxide-induced apoptosis in Cos-7 cells
por: Yoon, Ji-Young, et al.
Publicado: (2016)

Piperlongumine decreases cognitive impairment and improves hippocampal function in aged mice
por: Go, Jun, et al.
Publicado: (2018)

Piperlongumine Analogs Promote A549 Cell Apoptosis through Enhancing ROS Generation
por: Sun, Ai-Ling, et al.
Publicado: (2021)

Zearalenone Induces Apoptosis and Cytoprotective Autophagy in Chicken Granulosa Cells by PI3K-AKT-mTOR and MAPK Signaling Pathways
por: Zhu, Yifeng, et al.
Publicado: (2021)

Piperlongumine Induces Cellular Apoptosis and Autophagy via the ROS/Akt Signaling Pathway in Human Follicular Thyroid Cancer Cells
por: Lin, Tsung-Hsing, et al.
Publicado: (2023)

Asparaginase induces apoptosis and cytoprotective autophagy in chronic myeloid leukemia cells
por: Song, Ping, et al.
Publicado: (2015)

Apoptotic Effect of Tolfenamic Acid in KB Human Oral Cancer Cells: Possible Involvement of the p38 MAPK Pathway
por: Kim, Jun-Hee, et al.
Publicado: (2010)

Metabolic profile and safety of piperlongumine
por: de Lima Moreira, Fernanda, et al.
Publicado: (2016)

Piperlongumine Suppresses Proliferation of Human Oral Squamous Cell Carcinoma through Cell Cycle Arrest, Apoptosis and Senescence
por: Chen, San-Yuan, et al.
Publicado: (2016)

T-2 Toxin Induces Oxidative Stress, Apoptosis and Cytoprotective Autophagy in Chicken Hepatocytes
por: Yin, Huadong, et al.
Publicado: (2020)

Antrodia salmonea induces apoptosis and enhances cytoprotective autophagy in colon cancer cells
por: Yang, Hsin-Ling, et al.
Publicado: (2021)

Auranofin induces apoptosis by ROS-mediated ER stress and mitochondrial dysfunction and displayed synergistic lethality with piperlongumine in gastric cancer
por: Zou, Peng, et al.
Publicado: (2015)

P2RX7-MAPK1/2-SP1 axis inhibits MTOR independent HSPB1-mediated astroglial autophagy
por: Kim, Ji-Eun, et al.
Publicado: (2018)

Piperlongumine Induces Apoptosis and Synergizes with Cisplatin or Paclitaxel in Human Ovarian Cancer Cells
por: Gong, Li-Hua, et al.
Publicado: (2014)

Piperlongumine, a Novel TrxR1 Inhibitor, Induces Apoptosis in Hepatocellular Carcinoma Cells by ROS-Mediated ER Stress
por: Zhang, Qianqian, et al.
Publicado: (2019)

AKF-D52, a Synthetic Phenoxypyrimidine-Urea Derivative, Triggers Extrinsic/Intrinsic Apoptosis and Cytoprotective Autophagy in Human Non-Small Cell Lung Cancer Cells
por: Gil, Hyo-Sun, et al.
Publicado: (2021)

Propofol protects human keratinocytes from oxidative stress via autophagy expression
por: Yoon, Ji-Young, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_f90u2jbuc8b1te9uqug1t875fm