AMPK-Dependent YAP Inhibition Mediates the Protective Effect of Metformin against Obesity-Associated Endothelial Dysfunction and Inflammation

Hyperglycemia is a crucial risk factor for cardiovascular diseases. Chronic inflammation is a central characteristic of obesity, leading to many of its complications. Recent studies have shown that high glucose activates Yes-associated protein 1 (YAP) by suppressing AMPK activity in breast cancer ce...

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Detalles Bibliográficos
Autores principales: Kang, Lijing, Yi, Juanjuan, Lau, Chi-Wai, He, Lei, Chen, Qinghua, Xu, Suowen, Li, Jun, Xia, Yin, Zhang, Yuanting, Huang, Yu, Wang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525300/
https://www.ncbi.nlm.nih.gov/pubmed/37759984
http://dx.doi.org/10.3390/antiox12091681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525300/
https://www.ncbi.nlm.nih.gov/pubmed/37759984
http://dx.doi.org/10.3390/antiox12091681

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