Cargando…

Gossypetin Is a Novel Modulator of Inflammatory Cytokine Production and a Suppressor of Osteosarcoma Cell Growth

Osteosarcoma (OS) is a common childhood sarcoma, and its treatment is hindered by adverse effects, chemoresistance, and recurrence. Interleukin (IL)-6 production by tumors plays a significant role in inflammation, carcinogenesis, and metastasis. This study aimed to investigate the antiproliferative...

Descripción completa

Detalles Bibliográficos
Autores principales:	Proença, Carina, Rufino, Ana Teresa, Santos, Isabela, Albuquerque, Hélio M. T., Silva, Artur M. S., Fernandes, Eduarda, Ferreira de Oliveira, José Miguel P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525374/ https://www.ncbi.nlm.nih.gov/pubmed/37760046 http://dx.doi.org/10.3390/antiox12091744

Ejemplares similares

3′,4′-Dihydroxyflavonol Modulates the Cell Cycle in Cancer Cells: Implication as a Potential Combination Drug in Osteosarcoma
por: Ferreira de Oliveira, José Miguel P., et al.
Publicado: (2021)

Anticancer effects of gossypetin from Hibiscus sabdariffa in oral squamous cell carcinoma
por: HUANG, Ke, et al.
Publicado: (2023)

Anti-Atherosclerotic Effect of Gossypetin on Abnormal Vascular Smooth Muscle Cell Proliferation and Migration
por: Lin, Hui-Hsuan, et al.
Publicado: (2021)

2-Styrylchromones Prevent IL-1β-Induced Pro-Inflammatory Activation of Fibroblast-like Synoviocytes while Increasing COX-2 Expression †
por: Rufino, Ana Teresa, et al.
Publicado: (2023)

Gossypetin ameliorates 5xFAD spatial learning and memory through enhanced phagocytosis against Aβ
por: Jo, Kyung Won, et al.
Publicado: (2022)

Dataset of chicken-embryo blood cells exposed to quercetin, methyl methanesulfonate, or cadmium chloride
por: Ferreira de Oliveira, José Miguel P., et al.
Publicado: (2023)

A New Polyoxygenated Flavonol Gossypetin-3-O-β-d-Robinobioside from Caesalpinia gilliesii (Hook.) D. Dietr. and In Vivo Hepatoprotective, Anti-Inflammatory, and Anti-Ulcer Activities of the Leaf Methanol Extract
por: Emam, Mahmoud, et al.
Publicado: (2018)

Dogs with osteosarcoma have altered pro‐ and anti‐inflammatory cytokine profiles
por: Axiak‐Bechtel, Sandra M., et al.
Publicado: (2019)

Role of Suppressors of Cytokine Signaling 3 in Bone Inflammatory Responses
por: Gao, Anqi, et al.
Publicado: (2014)

α-Glucosidase inhibition by flavonoids: an in vitro and in silico structure–activity relationship study
por: Proença, Carina, et al.
Publicado: (2017)

Protective Role of Flavonoids against Intestinal Pro-Inflammatory Effects of Silver Nanoparticles
por: Rufino, Ana T., et al.
Publicado: (2021)

Isolation of Myricitrin and 3,5-di-O-Methyl Gossypetin from Syzygium samarangense and Evaluation of their Involvement in Protecting Keratinocytes against Oxidative Stress via Activation of the Nrf-2 Pathway
por: Sobeh, Mansour, et al.
Publicado: (2019)

Auranofin is a potent suppressor of osteosarcoma metastasis
por: Topkas, Eleni, et al.
Publicado: (2015)

HACE1 is a potential tumor suppressor in osteosarcoma
por: El-Naggar, Amal M, et al.
Publicado: (2019)

Evaluation of a flavonoids library for inhibition of pancreatic α-amylase towards a structure–activity relationship
por: Proença, Carina, et al.
Publicado: (2019)

Suppressors of cytokine signaling in tuberculosis
por: Lee, Shih-Wei, et al.
Publicado: (2017)

The Tumor Suppressor Role of miR-124 in Osteosarcoma
por: Geng, Shuo, et al.
Publicado: (2014)

Suppressors of Cytokine Signaling and Hepatocellular Carcinoma
por: Masuzaki, Ryota, et al.
Publicado: (2022)

Retraction: The Tumor Suppressor Role of miR-124 in Osteosarcoma
por: Geng, Shuo, et al.
Publicado: (2019)

Suppressor of Cytokine Signalling 5 (SOCS5) Modulates Inflammatory Responses during Alphavirus Infection
por: Kedzierski, Lukasz, et al.
Publicado: (2022)

The Role of Suppressors of Cytokine Signalling in Human Neoplasms
por: Sasi, Walid, et al.
Publicado: (2014)

The ARF Tumor Suppressor Regulates Bone Remodeling and Osteosarcoma Development in Mice
por: Rauch, Daniel A., et al.
Publicado: (2010)

Prognostic value of tumor suppressors in osteosarcoma before and after neoadjuvant chemotherapy
por: Robl, Bernhard, et al.
Publicado: (2015)

AMPH-1 As A Critical Tumor Suppressor That Inhibits Osteosarcoma Progression
por: Zhang, Haiyun, et al.
Publicado: (2019)

Slit-Robo GTPase-Activating Protein 2 as a metastasis suppressor in osteosarcoma
por: Marko, Tracy A., et al.
Publicado: (2016)

An In Silico and an In Vitro Inhibition Analysis of Glycogen Phosphorylase by Flavonoids, Styrylchromones, and Pyrazoles
por: Rocha, Sónia, et al.
Publicado: (2022)

Unmasking an inflammatory suppressor
por: Bashyam, Hema
Publicado: (2008)

Alendronic Acid as Ionic Liquid: New Perspective on Osteosarcoma
por: Teixeira, Sónia, et al.
Publicado: (2020)

Suppressor of cytokine signalling gene expression is elevated in breast carcinoma
por: Raccurt, M, et al.
Publicado: (2003)

Mechanism of inflammatory response in associated comorbidities in COVID-19
por: de Lucena, Thays Maria Costa, et al.
Publicado: (2020)

Chromeno[3,4-b]xanthones as First-in-Class AChE and Aβ Aggregation Dual-Inhibitors
por: Malafaia, Daniela, et al.
Publicado: (2021)

Low back pain, obesity, and inflammatory markers: exercise as potential treatment
por: da Cruz Fernandes, Isabela Maia, et al.
Publicado: (2018)

A Large Gastric Inflammatory Fibroid Polyp
por: Pinto-Pais, Teresa, et al.
Publicado: (2015)

Tumor Suppressor WWOX inhibits osteosarcoma metastasis by modulating RUNX2 function
por: Del Mare, Sara, et al.
Publicado: (2015)

The metastasis suppressor gene KISS-1 regulates osteosarcoma apoptosis and autophagy processes
por: Yin, Yiran, et al.
Publicado: (2017)

p27/Kip1 functions as a tumor suppressor and oncoprotein in osteosarcoma
por: Currier, Arthur W., et al.
Publicado: (2019)

Cross-species genomics identifies DLG2 as a tumor suppressor in osteosarcoma
por: Shao, Yang W., et al.
Publicado: (2018)

Regulation of liver regeneration and hepatocarcinogenesis by suppressor of cytokine signaling 3
por: Riehle, Kimberly J., et al.
Publicado: (2008)

Role of Suppressor of Cytokine Signaling-1 In Murine Atherosclerosis
por: Grothusen, Christina, et al.
Publicado: (2012)

Cholesterol-Based Compounds: Recent Advances in Synthesis and Applications
por: Albuquerque, Hélio M. T., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_mde3e7r1c1n5pio506n3tn2m64