Cargando…

Protein-Bound Uremic Toxins in Senescence and Kidney Fibrosis

Chronic kidney disease (CKD) is a progressive condition of kidney dysfunction due to diverse causes of injury. In healthy kidneys, protein-bound uremic toxins (PBUTs) are cleared from the systemic circulation by proximal tubule cells through the concerted action of plasma membrane transporters that...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Yi, Mihajlovic, Milos, Masereeuw, Rosalinde
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525416/ https://www.ncbi.nlm.nih.gov/pubmed/37760849 http://dx.doi.org/10.3390/biomedicines11092408

Ejemplares similares

The Uremic Toxin Indoxyl Sulfate Accelerates Senescence in Kidney Proximal Tubule Cells
por: Yang, Yi, et al.
Publicado: (2023)

Protein-Bound Uremic Toxins Induce Reactive Oxygen Species-Dependent and Inflammasome-Mediated IL-1β Production in Kidney Proximal Tubule Cells
por: Mihajlovic, Milos, et al.
Publicado: (2021)

Selective Transport of Protein-Bound Uremic Toxins in Erythrocytes
por: Deltombe, Olivier, et al.
Publicado: (2019)

Animal Models for Studying Protein-Bound Uremic Toxin Removal—A Systematic Review
por: Ahmed, Sabbir, et al.
Publicado: (2023)

The Dual Roles of Protein-Bound Solutes as Toxins and Signaling Molecules in Uremia
por: Masereeuw, Rosalinde
Publicado: (2022)

Effects of an SGLT Inhibitor on the Production, Toxicity, and Elimination of Gut-Derived Uremic Toxins: A Call for Additional Evidence
por: Evenepoel, Pieter, et al.
Publicado: (2022)

Gut-Derived Protein-Bound Uremic Toxins
por: Graboski, Amanda L., et al.
Publicado: (2020)

Bioengineered Kidney Tubules Efficiently Clear Uremic Toxins in Experimental Dialysis Conditions
por: Faria, João, et al.
Publicado: (2023)

Protein-Bound Uremic Toxins in Hemodialysis Patients Relate to Residual Kidney Function, Are Not Influenced by Convective Transport, and Do Not Relate to Outcome
por: van Gelder, Maaike K., et al.
Publicado: (2020)

A Human Conditionally Immortalized Proximal Tubule Epithelial Cell Line as a Novel Model for Studying Senescence and Response to Senolytics
por: Yang, Yi, et al.
Publicado: (2022)

Drugs Commonly Applied to Kidney Patients May Compromise Renal Tubular Uremic Toxins Excretion
por: Mihaila, Silvia M., et al.
Publicado: (2020)

The Role of Gut-Derived, Protein-Bound Uremic Toxins in the Cardiovascular Complications of Acute Kidney Injury
por: Caillard, Pauline, et al.
Publicado: (2022)

Adsorption- and Displacement-Based Approaches for the Removal of Protein-Bound Uremic Toxins
por: Rodrigues, Flávia S. C., et al.
Publicado: (2023)

Passage Number-Induced Replicative Senescence Modulates the Endothelial Cell Response to Protein-Bound Uremic Toxins
por: Guerrero, Fatima, et al.
Publicado: (2021)

Uremic Toxins and Protein-Bound Therapeutics in AKI and CKD: Up-to-Date Evidence
por: Chen, Jia-Huang, et al.
Publicado: (2021)

Protein-bound uremic toxins impaired mitochondrial dynamics and functions
por: Sun, Chiao-Yin, et al.
Publicado: (2017)

Role of Vitamin D in Maintaining Renal Epithelial Barrier Function in Uremic Conditions
por: Mihajlovic, Milos, et al.
Publicado: (2017)

Association between Protein-Bound Uremic Toxins and Asymptomatic Cardiac Dysfunction in Patients with Chronic Kidney Disease
por: Chinnappa, Shanmugakumar, et al.
Publicado: (2018)

Protein-Bound Uremic Toxins: New Culprits of Cardiovascular Events in Chronic Kidney Disease Patients
por: Ito, Shunsuke, et al.
Publicado: (2014)

Bioengineered kidney tubules efficiently excrete uremic toxins
por: Jansen, J., et al.
Publicado: (2016)

Precision Hemodialysis Using Sorbents to Remove Protein-Bound Uremic Toxins
por: Ash, Stephen R.
Publicado: (2023)

Protein-Bound Uremic Toxins: New Insight from Clinical Studies
por: Liabeuf, Sophie, et al.
Publicado: (2011)

Protein-Bound Uremic Toxin Profiling as a Tool to Optimize Hemodialysis
por: Eloot, Sunny, et al.
Publicado: (2016)

Uremic Toxins Induce ET-1 Release by Human Proximal Tubule Cells, which Regulates Organic Cation Uptake Time-Dependently
por: Schophuizen, Carolien M. S., et al.
Publicado: (2015)

Removal of Protein-Bound Uremic Toxins Using Binding Competitors in Hemodialysis: A Narrative Review
por: Maheshwari, Vaibhav, et al.
Publicado: (2021)

The Medium Cut-Off Membrane Does Not Lower Protein-Bound Uremic Toxins
por: Kim, Yang Gyun, et al.
Publicado: (2022)

Uremic Toxins Inhibit Transport by Breast Cancer Resistance Protein and Multidrug Resistance Protein 4 at Clinically Relevant Concentrations
por: Mutsaers, Henricus A. M., et al.
Publicado: (2011)

Unambiguous Characterization of p-Cresyl Sulfate, a Protein-Bound Uremic Toxin, as Biomarker of Heart and Kidney Disease
por: Paroni, Rita, et al.
Publicado: (2019)

Protein-bound uremic toxins are associated with cognitive function among patients undergoing maintenance hemodialysis
por: Lin, Yi-Ting, et al.
Publicado: (2019)

Food-Derived Uremic Toxins in Chronic Kidney Disease
por: Lauriola, Mara, et al.
Publicado: (2023)

Uremic Toxins and Clinical Outcomes: The Impact of Kidney Transplantation
por: Liabeuf, Sophie, et al.
Publicado: (2018)

Role of Uremic Toxins for Kidney, Cardiovascular, and Bone Dysfunction
por: Fujii, Hideki, et al.
Publicado: (2018)

Detailing Protein-Bound Uremic Toxin Interaction Mechanisms with Human Serum Albumin in the Pursuit of Designing Competitive Binders
por: Dehghan Niestanak, Vida, et al.
Publicado: (2023)

Effect of Low Protein Diet Supplemented with Ketoanalogs on Endothelial Function and Protein-Bound Uremic Toxins in Patients with Chronic Kidney Disease
por: Chang, George, et al.
Publicado: (2023)

Uremic Solutes in Chronic Kidney Disease and Their Role in Progression
por: van den Brand, Jan A. J. G., et al.
Publicado: (2016)

Immunosenescence and Immune Exhaustion Are Associated with Levels of Protein-Bound Uremic Toxins in Patients on Hemodialysis
por: Tourountzis, Theodoros, et al.
Publicado: (2023)

A novel mathematical model of protein-bound uremic toxin kinetics during hemodialysis
por: Maheshwari, Vaibhav, et al.
Publicado: (2017)

Tryptophan-Derived Uremic Toxins and Thrombosis in Chronic Kidney Disease
por: Addi, Tawfik, et al.
Publicado: (2018)

The Therapeutic Strategies for Uremic Toxins Control in Chronic Kidney Disease
por: Lu, Ping-Hsun, et al.
Publicado: (2021)

The Potential Influence of Uremic Toxins on the Homeostasis of Bones and Muscles in Chronic Kidney Disease
por: Hung, Kuo-Chin, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_r9srofeok91t8phlfchpi56keb