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Localized Refractive Changes Induced by Symmetric and Progressive Asymmetric Intracorneal Ring Segments Assessed with a 3D Finite-Element Model

To build a representative 3D finite element model (FEM) for intracorneal ring segment (ICRS) implantation and to investigate localized optical changes induced by different ICRS geometries, a hyperelastic shell FEM was developed to compare the effect of symmetric and progressive asymmetric ICRS desig...

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Autores principales: García de Oteyza, Gonzalo, Álvarez de Toledo, Juan, Barraquer, Rafael I., Kling, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525444/
https://www.ncbi.nlm.nih.gov/pubmed/37760115
http://dx.doi.org/10.3390/bioengineering10091014
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author García de Oteyza, Gonzalo
Álvarez de Toledo, Juan
Barraquer, Rafael I.
Kling, Sabine
author_facet García de Oteyza, Gonzalo
Álvarez de Toledo, Juan
Barraquer, Rafael I.
Kling, Sabine
author_sort García de Oteyza, Gonzalo
collection PubMed
description To build a representative 3D finite element model (FEM) for intracorneal ring segment (ICRS) implantation and to investigate localized optical changes induced by different ICRS geometries, a hyperelastic shell FEM was developed to compare the effect of symmetric and progressive asymmetric ICRS designs in a generic healthy and asymmetric keratoconic (KC) cornea. The resulting deformed geometry was assessed in terms of average curvature via a biconic fit, sagittal curvature (K), and optical aberrations via Zernike polynomials. The sagittal curvature map showed a locally restricted flattening interior to the ring (Kmax −11 to −25 dpt) and, in the KC cornea, an additional local steepening on the opposite half of the cornea (Kmax up to +1.9 dpt). Considering the optical aberrations present in the model of the KC cornea, the progressive ICRS corrected vertical coma (−3.42 vs. −3.13 µm); horizontal coma (−0.67 vs. 0.36 µm); and defocus (2.90 vs. 2.75 µm), oblique trefoil (−0.54 vs. −0.08 µm), and oblique secondary astigmatism (0.48 vs. −0.09 µm) aberrations stronger than the symmetric ICRS. Customized ICRS designs inspired by the underlying KC phenotype have the potential to achieve more tailored refractive corrections, particularly in asymmetric keratoconus patterns.
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spelling pubmed-105254442023-09-28 Localized Refractive Changes Induced by Symmetric and Progressive Asymmetric Intracorneal Ring Segments Assessed with a 3D Finite-Element Model García de Oteyza, Gonzalo Álvarez de Toledo, Juan Barraquer, Rafael I. Kling, Sabine Bioengineering (Basel) Article To build a representative 3D finite element model (FEM) for intracorneal ring segment (ICRS) implantation and to investigate localized optical changes induced by different ICRS geometries, a hyperelastic shell FEM was developed to compare the effect of symmetric and progressive asymmetric ICRS designs in a generic healthy and asymmetric keratoconic (KC) cornea. The resulting deformed geometry was assessed in terms of average curvature via a biconic fit, sagittal curvature (K), and optical aberrations via Zernike polynomials. The sagittal curvature map showed a locally restricted flattening interior to the ring (Kmax −11 to −25 dpt) and, in the KC cornea, an additional local steepening on the opposite half of the cornea (Kmax up to +1.9 dpt). Considering the optical aberrations present in the model of the KC cornea, the progressive ICRS corrected vertical coma (−3.42 vs. −3.13 µm); horizontal coma (−0.67 vs. 0.36 µm); and defocus (2.90 vs. 2.75 µm), oblique trefoil (−0.54 vs. −0.08 µm), and oblique secondary astigmatism (0.48 vs. −0.09 µm) aberrations stronger than the symmetric ICRS. Customized ICRS designs inspired by the underlying KC phenotype have the potential to achieve more tailored refractive corrections, particularly in asymmetric keratoconus patterns. MDPI 2023-08-27 /pmc/articles/PMC10525444/ /pubmed/37760115 http://dx.doi.org/10.3390/bioengineering10091014 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
García de Oteyza, Gonzalo
Álvarez de Toledo, Juan
Barraquer, Rafael I.
Kling, Sabine
Localized Refractive Changes Induced by Symmetric and Progressive Asymmetric Intracorneal Ring Segments Assessed with a 3D Finite-Element Model
title Localized Refractive Changes Induced by Symmetric and Progressive Asymmetric Intracorneal Ring Segments Assessed with a 3D Finite-Element Model
title_full Localized Refractive Changes Induced by Symmetric and Progressive Asymmetric Intracorneal Ring Segments Assessed with a 3D Finite-Element Model
title_fullStr Localized Refractive Changes Induced by Symmetric and Progressive Asymmetric Intracorneal Ring Segments Assessed with a 3D Finite-Element Model
title_full_unstemmed Localized Refractive Changes Induced by Symmetric and Progressive Asymmetric Intracorneal Ring Segments Assessed with a 3D Finite-Element Model
title_short Localized Refractive Changes Induced by Symmetric and Progressive Asymmetric Intracorneal Ring Segments Assessed with a 3D Finite-Element Model
title_sort localized refractive changes induced by symmetric and progressive asymmetric intracorneal ring segments assessed with a 3d finite-element model
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525444/
https://www.ncbi.nlm.nih.gov/pubmed/37760115
http://dx.doi.org/10.3390/bioengineering10091014
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