Cargando…

The Effect of Three Desensitizing Toothpastes on Dentinal Tubules Occlusion and on Dentin Hardness

There are two main methods used for dentin hypersensitivity (DH) treatment: dentinal tubule occlusion and blockage of nerve activity. Dentifrices are the most common vehicles for active ingredients used for DH treatment. The aim of this study was to evaluate the efficacy of three toothpastes on dent...

Descripción completa

Detalles Bibliográficos
Autores principales: Bologa, Emilia, Stoleriu, Simona, Nica, Irina, Tărăboanță, Ionuț, Georgescu, Andrei, Matei, Ruxandra Ilinca, Andrian, Sorin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525594/
https://www.ncbi.nlm.nih.gov/pubmed/37760904
http://dx.doi.org/10.3390/biomedicines11092464
_version_ 1785110821701943296
author Bologa, Emilia
Stoleriu, Simona
Nica, Irina
Tărăboanță, Ionuț
Georgescu, Andrei
Matei, Ruxandra Ilinca
Andrian, Sorin
author_facet Bologa, Emilia
Stoleriu, Simona
Nica, Irina
Tărăboanță, Ionuț
Georgescu, Andrei
Matei, Ruxandra Ilinca
Andrian, Sorin
author_sort Bologa, Emilia
collection PubMed
description There are two main methods used for dentin hypersensitivity (DH) treatment: dentinal tubule occlusion and blockage of nerve activity. Dentifrices are the most common vehicles for active ingredients used for DH treatment. The aim of this study was to evaluate the efficacy of three toothpastes on dentinal tubule occlusion, mineral acquisition, and dentin hardness. Forty human dentin disks were submerged in 40% citric acid for 30 s and then exposed to tooth brushing for 2 min twice a day for 14 days using three toothpastes: Dontodent Sensitive (group 1), Dr. Wolff’s Biorepair (group 2), and Sensodyne Repair and Protect (group 3). In the control group (group 4), the samples were brushed with water. All of the samples were evaluated using scanning electron microscopy (SEM), energy-dispersive X-ray (EDX), and Vickers dentin hardness determination. On SEM images, the degree of dentinal tubule occlusion was assessed using a five-grade scale. The mean score values in groups 1–4 were 3.60 ± 0.69, 2.20 ± 0.91, 2.30 ± 1.16, and 5.00 ± 0.00, significantly higher in study groups when compared to the control group (Kruskal Wallis test p < 0.05). EDX evaluation showed significantly higher calcium and phosphorus concentrations in groups 1 and 3 when compared to control group d. The mean values of Vickers dentin hardness numbers in groups 1–4 were 243.03 ± 10.014, 327.38 ± 56.65, 260.29 ± 37.69, and 225.83 ± 29.93, respectively. No statistically significant results were obtained when comparing the hardness mean values in groups (Kruskal-Wallis statistical test, p = 0.372 > 0.05). All three toothpastes tested demonstrated significant occlusion of dentinal tubules. Dontodent Sensitive and Sensodyne Repair and Protect toothpastes enhanced the calcium and phosphorus content of the dentin surface. None of the toothpastes increased dentin hardness as a result of mineral acquisition.
format Online
Article
Text
id pubmed-10525594
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-105255942023-09-28 The Effect of Three Desensitizing Toothpastes on Dentinal Tubules Occlusion and on Dentin Hardness Bologa, Emilia Stoleriu, Simona Nica, Irina Tărăboanță, Ionuț Georgescu, Andrei Matei, Ruxandra Ilinca Andrian, Sorin Biomedicines Article There are two main methods used for dentin hypersensitivity (DH) treatment: dentinal tubule occlusion and blockage of nerve activity. Dentifrices are the most common vehicles for active ingredients used for DH treatment. The aim of this study was to evaluate the efficacy of three toothpastes on dentinal tubule occlusion, mineral acquisition, and dentin hardness. Forty human dentin disks were submerged in 40% citric acid for 30 s and then exposed to tooth brushing for 2 min twice a day for 14 days using three toothpastes: Dontodent Sensitive (group 1), Dr. Wolff’s Biorepair (group 2), and Sensodyne Repair and Protect (group 3). In the control group (group 4), the samples were brushed with water. All of the samples were evaluated using scanning electron microscopy (SEM), energy-dispersive X-ray (EDX), and Vickers dentin hardness determination. On SEM images, the degree of dentinal tubule occlusion was assessed using a five-grade scale. The mean score values in groups 1–4 were 3.60 ± 0.69, 2.20 ± 0.91, 2.30 ± 1.16, and 5.00 ± 0.00, significantly higher in study groups when compared to the control group (Kruskal Wallis test p < 0.05). EDX evaluation showed significantly higher calcium and phosphorus concentrations in groups 1 and 3 when compared to control group d. The mean values of Vickers dentin hardness numbers in groups 1–4 were 243.03 ± 10.014, 327.38 ± 56.65, 260.29 ± 37.69, and 225.83 ± 29.93, respectively. No statistically significant results were obtained when comparing the hardness mean values in groups (Kruskal-Wallis statistical test, p = 0.372 > 0.05). All three toothpastes tested demonstrated significant occlusion of dentinal tubules. Dontodent Sensitive and Sensodyne Repair and Protect toothpastes enhanced the calcium and phosphorus content of the dentin surface. None of the toothpastes increased dentin hardness as a result of mineral acquisition. MDPI 2023-09-05 /pmc/articles/PMC10525594/ /pubmed/37760904 http://dx.doi.org/10.3390/biomedicines11092464 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bologa, Emilia
Stoleriu, Simona
Nica, Irina
Tărăboanță, Ionuț
Georgescu, Andrei
Matei, Ruxandra Ilinca
Andrian, Sorin
The Effect of Three Desensitizing Toothpastes on Dentinal Tubules Occlusion and on Dentin Hardness
title The Effect of Three Desensitizing Toothpastes on Dentinal Tubules Occlusion and on Dentin Hardness
title_full The Effect of Three Desensitizing Toothpastes on Dentinal Tubules Occlusion and on Dentin Hardness
title_fullStr The Effect of Three Desensitizing Toothpastes on Dentinal Tubules Occlusion and on Dentin Hardness
title_full_unstemmed The Effect of Three Desensitizing Toothpastes on Dentinal Tubules Occlusion and on Dentin Hardness
title_short The Effect of Three Desensitizing Toothpastes on Dentinal Tubules Occlusion and on Dentin Hardness
title_sort effect of three desensitizing toothpastes on dentinal tubules occlusion and on dentin hardness
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525594/
https://www.ncbi.nlm.nih.gov/pubmed/37760904
http://dx.doi.org/10.3390/biomedicines11092464
work_keys_str_mv AT bologaemilia theeffectofthreedesensitizingtoothpastesondentinaltubulesocclusionandondentinhardness
AT stoleriusimona theeffectofthreedesensitizingtoothpastesondentinaltubulesocclusionandondentinhardness
AT nicairina theeffectofthreedesensitizingtoothpastesondentinaltubulesocclusionandondentinhardness
AT taraboantaionut theeffectofthreedesensitizingtoothpastesondentinaltubulesocclusionandondentinhardness
AT georgescuandrei theeffectofthreedesensitizingtoothpastesondentinaltubulesocclusionandondentinhardness
AT mateiruxandrailinca theeffectofthreedesensitizingtoothpastesondentinaltubulesocclusionandondentinhardness
AT andriansorin theeffectofthreedesensitizingtoothpastesondentinaltubulesocclusionandondentinhardness
AT bologaemilia effectofthreedesensitizingtoothpastesondentinaltubulesocclusionandondentinhardness
AT stoleriusimona effectofthreedesensitizingtoothpastesondentinaltubulesocclusionandondentinhardness
AT nicairina effectofthreedesensitizingtoothpastesondentinaltubulesocclusionandondentinhardness
AT taraboantaionut effectofthreedesensitizingtoothpastesondentinaltubulesocclusionandondentinhardness
AT georgescuandrei effectofthreedesensitizingtoothpastesondentinaltubulesocclusionandondentinhardness
AT mateiruxandrailinca effectofthreedesensitizingtoothpastesondentinaltubulesocclusionandondentinhardness
AT andriansorin effectofthreedesensitizingtoothpastesondentinaltubulesocclusionandondentinhardness