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Dosing Optimization of Posaconazole in Lung-Transplant Recipients Based on Population Pharmacokinetic Model

Although posaconazole tablets show relatively low variability in pharmacokinetics (PK), the proportion of patients achieving the PK/PD target at the approved uniform dose for both prophylaxis and therapy is not satisfactory. The aim of this study was to develop a posaconazole population PK model in...

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Detalles Bibliográficos
Autores principales: Dvořáčková, Eliška, Šíma, Martin, Zajacová, Andrea, Vyskočilová, Kristýna, Kotowski, Tereza, Dunovská, Kateřina, Klapková, Eva, Havlín, Jan, Lischke, Robert, Slanař, Ondřej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525625/
https://www.ncbi.nlm.nih.gov/pubmed/37760696
http://dx.doi.org/10.3390/antibiotics12091399