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Characterization of the Intracellular Acidity Regulation of Brain Tumor Cells and Consequences for Therapeutic Optimization of Temozolomide
SIMPLE SUMMARY: Tumor cells have high levels of metabolic activity, which makes the environment around them more acidic. This acidic environment encourages the aggressiveness and invasiveness of the tumor, which are linked to a worse prognosis. Cancer cells may control their internal acidity in diff...
Autores principales: | Tafech, Alaa, Jacquet, Pierre, Beaujean, Céline, Fertin, Arnold, Usson, Yves, Stéphanou, Angélique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525637/ https://www.ncbi.nlm.nih.gov/pubmed/37759620 http://dx.doi.org/10.3390/biology12091221 |
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