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Characterization of the Intracellular Acidity Regulation of Brain Tumor Cells and Consequences for Therapeutic Optimization of Temozolomide

SIMPLE SUMMARY: Tumor cells have high levels of metabolic activity, which makes the environment around them more acidic. This acidic environment encourages the aggressiveness and invasiveness of the tumor, which are linked to a worse prognosis. Cancer cells may control their internal acidity in diff...

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Detalles Bibliográficos
Autores principales: Tafech, Alaa, Jacquet, Pierre, Beaujean, Céline, Fertin, Arnold, Usson, Yves, Stéphanou, Angélique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525637/
https://www.ncbi.nlm.nih.gov/pubmed/37759620
http://dx.doi.org/10.3390/biology12091221

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