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The Antioxidant and Prebiotic Activities of Mixtures Honey/Biomimetic NaDES and Polyphenols Show Differences between Honeysuckle and Raspberry Extracts
In our previous research, we demonstrated that honey and its biomimetic natural deep eutectic solvent (NaDES) modulate the antioxidant activity (AOA) of the raspberry extract (RE). In this study, we evaluated the AOA behaviour of the mixture honey/NaDES–honeysuckle (Lonicera caprifolium, LFL) extrac...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525646/ https://www.ncbi.nlm.nih.gov/pubmed/37759982 http://dx.doi.org/10.3390/antiox12091678 |
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author | Dimitriu, Luminița Constantinescu-Aruxandei, Diana Preda, Daniel Moraru, Ionuț Băbeanu, Narcisa Elena Oancea, Florin |
author_facet | Dimitriu, Luminița Constantinescu-Aruxandei, Diana Preda, Daniel Moraru, Ionuț Băbeanu, Narcisa Elena Oancea, Florin |
author_sort | Dimitriu, Luminița |
collection | PubMed |
description | In our previous research, we demonstrated that honey and its biomimetic natural deep eutectic solvent (NaDES) modulate the antioxidant activity (AOA) of the raspberry extract (RE). In this study, we evaluated the AOA behaviour of the mixture honey/NaDES–honeysuckle (Lonicera caprifolium, LFL) extract and compared it with the mixture honey/NaDES–RE. These two extracts have similar major flavonoids and hydroxycinnamic acid compounds but differ in their total content and the presence of anthocyanins in RE. Therefore, it was of interest to see if the modulation of the LFL polyphenols by honey/NaDES was similar to that of RE. We also evaluated the prebiotic activity of these mixtures and individual components on Limosilactobacillus reuteri DSM 20016. Although honey/NaDES modulated the AOA of both extracts, from synergism to antagonism, the modulation was different between the two extracts for some AOA activities. Honey/NaDES mixtures enriched with LFL and RE did not show significant differences in bacterial growth stimulation. However, at a concentration of 45 mg/mL, the honey -LFL mixture exhibited a higher effect compared to the honey–RE mixture. The antioxidant and prebiotic properties of mixtures between honey and polyphenol-rich extracts are determined by multiple interactions in complex chemical systems. |
format | Online Article Text |
id | pubmed-10525646 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-105256462023-09-28 The Antioxidant and Prebiotic Activities of Mixtures Honey/Biomimetic NaDES and Polyphenols Show Differences between Honeysuckle and Raspberry Extracts Dimitriu, Luminița Constantinescu-Aruxandei, Diana Preda, Daniel Moraru, Ionuț Băbeanu, Narcisa Elena Oancea, Florin Antioxidants (Basel) Article In our previous research, we demonstrated that honey and its biomimetic natural deep eutectic solvent (NaDES) modulate the antioxidant activity (AOA) of the raspberry extract (RE). In this study, we evaluated the AOA behaviour of the mixture honey/NaDES–honeysuckle (Lonicera caprifolium, LFL) extract and compared it with the mixture honey/NaDES–RE. These two extracts have similar major flavonoids and hydroxycinnamic acid compounds but differ in their total content and the presence of anthocyanins in RE. Therefore, it was of interest to see if the modulation of the LFL polyphenols by honey/NaDES was similar to that of RE. We also evaluated the prebiotic activity of these mixtures and individual components on Limosilactobacillus reuteri DSM 20016. Although honey/NaDES modulated the AOA of both extracts, from synergism to antagonism, the modulation was different between the two extracts for some AOA activities. Honey/NaDES mixtures enriched with LFL and RE did not show significant differences in bacterial growth stimulation. However, at a concentration of 45 mg/mL, the honey -LFL mixture exhibited a higher effect compared to the honey–RE mixture. The antioxidant and prebiotic properties of mixtures between honey and polyphenol-rich extracts are determined by multiple interactions in complex chemical systems. MDPI 2023-08-28 /pmc/articles/PMC10525646/ /pubmed/37759982 http://dx.doi.org/10.3390/antiox12091678 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Dimitriu, Luminița Constantinescu-Aruxandei, Diana Preda, Daniel Moraru, Ionuț Băbeanu, Narcisa Elena Oancea, Florin The Antioxidant and Prebiotic Activities of Mixtures Honey/Biomimetic NaDES and Polyphenols Show Differences between Honeysuckle and Raspberry Extracts |
title | The Antioxidant and Prebiotic Activities of Mixtures Honey/Biomimetic NaDES and Polyphenols Show Differences between Honeysuckle and Raspberry Extracts |
title_full | The Antioxidant and Prebiotic Activities of Mixtures Honey/Biomimetic NaDES and Polyphenols Show Differences between Honeysuckle and Raspberry Extracts |
title_fullStr | The Antioxidant and Prebiotic Activities of Mixtures Honey/Biomimetic NaDES and Polyphenols Show Differences between Honeysuckle and Raspberry Extracts |
title_full_unstemmed | The Antioxidant and Prebiotic Activities of Mixtures Honey/Biomimetic NaDES and Polyphenols Show Differences between Honeysuckle and Raspberry Extracts |
title_short | The Antioxidant and Prebiotic Activities of Mixtures Honey/Biomimetic NaDES and Polyphenols Show Differences between Honeysuckle and Raspberry Extracts |
title_sort | antioxidant and prebiotic activities of mixtures honey/biomimetic nades and polyphenols show differences between honeysuckle and raspberry extracts |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525646/ https://www.ncbi.nlm.nih.gov/pubmed/37759982 http://dx.doi.org/10.3390/antiox12091678 |
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