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Evaluation of Molecular Simulations and Deep Learning Prediction of Antibodies’ Recognition of TRBC1 and TRBC2

T cell receptor β-chain constant (TRBC) is a promising class of cancer targets consisting of two highly homologous proteins, TRBC1 and TRBC2. Developing targeted antibody therapeutics against TRBC1 or TRBC2 is expected to eradicate the malignant T cells and preserve half of the normal T cells. Recen...

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Detalles Bibliográficos
Autores principales: Zeng, Xincheng, Wang, Tianqun, Kang, Yue, Bai, Ganggang, Ma, Buyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525649/
https://www.ncbi.nlm.nih.gov/pubmed/37753972
http://dx.doi.org/10.3390/antib12030058

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