Cargando…
Melatonin Restores Autophagic Flux by Activating the Sirt3/TFEB Signaling Pathway to Attenuate Doxorubicin-Induced Cardiomyopathy
Doxorubicin (DOX) chemotherapy in cancer patients increases the risk of the occurrence of cardiac dysfunction and even results in congestive heart failure. Despite the great progress of pathology in DOX-induced cardiomyopathy, the underlying molecular mechanisms remain elusive. Here, we investigate...
Autores principales: | Ma, Yanyan, Ma, Jipeng, Lu, Linhe, Xiong, Xiang, Shao, Yalan, Ren, Jun, Yang, Jian, Liu, Jiankang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525655/ https://www.ncbi.nlm.nih.gov/pubmed/37760018 http://dx.doi.org/10.3390/antiox12091716 |
Ejemplares similares
-
Restoring autophagic flux attenuates cochlear spiral ganglion neuron degeneration by promoting TFEB nuclear translocation via inhibiting MTOR
por: Ye, Bin, et al.
Publicado: (2019) -
Squaramide-based synthetic chloride transporters activate TFEB but block autophagic flux
por: Zhang, Shaoyi, et al.
Publicado: (2019) -
Disruption of ROCK1 gene restores autophagic flux and mitigates doxorubicin-induced cardiotoxicity
por: Shi, Jianjian, et al.
Publicado: (2018) -
Astragalus polysaccharide restores autophagic flux and improves cardiomyocyte function in doxorubicin-induced cardiotoxicity
por: Cao, Yuan, et al.
Publicado: (2016) -
Author Correction: Squaramide-based synthetic chloride transporters activate TFEB but block autophagic flux
por: Zhang, Shaoyi, et al.
Publicado: (2019)