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Stress Urinary Incontinence: An Unsolved Clinical Challenge
Stress urinary incontinence is still a frequent problem for women and men, which leads to pronounced impairment of the quality of life and withdrawal from the social environment. Modern diagnostics and therapy improved the situation for individuals affected. But there are still limits, including the...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525672/ https://www.ncbi.nlm.nih.gov/pubmed/37760927 http://dx.doi.org/10.3390/biomedicines11092486 |
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author | Harland, Niklas Walz, Simon Eberli, Daniel Schmid, Florian A. Aicher, Wilhelm K. Stenzl, Arnulf Amend, Bastian |
author_facet | Harland, Niklas Walz, Simon Eberli, Daniel Schmid, Florian A. Aicher, Wilhelm K. Stenzl, Arnulf Amend, Bastian |
author_sort | Harland, Niklas |
collection | PubMed |
description | Stress urinary incontinence is still a frequent problem for women and men, which leads to pronounced impairment of the quality of life and withdrawal from the social environment. Modern diagnostics and therapy improved the situation for individuals affected. But there are still limits, including the correct diagnosis of incontinence and its pathophysiology, as well as the therapeutic algorithms. In most cases, patients are treated with a first-line regimen of drugs, possibly in combination with specific exercises and electrophysiological stimulation. When conservative options are exhausted, minimally invasive surgical therapies are indicated. However, standard surgeries, especially the application of implants, do not pursue any causal therapy. Non-absorbable meshes and ligaments have fallen into disrepute due to complications. In numerous countries, classic techniques such as colposuspension have been revived to avoid implants. Except for tapes in the treatment of stress urinary incontinence in women, the literature on randomized controlled studies is insufficient. This review provides an update on pharmacological and surgical treatment options for stress urinary incontinence; it highlights limitations and formulates wishes for the future from a clinical perspective. |
format | Online Article Text |
id | pubmed-10525672 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-105256722023-09-28 Stress Urinary Incontinence: An Unsolved Clinical Challenge Harland, Niklas Walz, Simon Eberli, Daniel Schmid, Florian A. Aicher, Wilhelm K. Stenzl, Arnulf Amend, Bastian Biomedicines Review Stress urinary incontinence is still a frequent problem for women and men, which leads to pronounced impairment of the quality of life and withdrawal from the social environment. Modern diagnostics and therapy improved the situation for individuals affected. But there are still limits, including the correct diagnosis of incontinence and its pathophysiology, as well as the therapeutic algorithms. In most cases, patients are treated with a first-line regimen of drugs, possibly in combination with specific exercises and electrophysiological stimulation. When conservative options are exhausted, minimally invasive surgical therapies are indicated. However, standard surgeries, especially the application of implants, do not pursue any causal therapy. Non-absorbable meshes and ligaments have fallen into disrepute due to complications. In numerous countries, classic techniques such as colposuspension have been revived to avoid implants. Except for tapes in the treatment of stress urinary incontinence in women, the literature on randomized controlled studies is insufficient. This review provides an update on pharmacological and surgical treatment options for stress urinary incontinence; it highlights limitations and formulates wishes for the future from a clinical perspective. MDPI 2023-09-07 /pmc/articles/PMC10525672/ /pubmed/37760927 http://dx.doi.org/10.3390/biomedicines11092486 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Harland, Niklas Walz, Simon Eberli, Daniel Schmid, Florian A. Aicher, Wilhelm K. Stenzl, Arnulf Amend, Bastian Stress Urinary Incontinence: An Unsolved Clinical Challenge |
title | Stress Urinary Incontinence: An Unsolved Clinical Challenge |
title_full | Stress Urinary Incontinence: An Unsolved Clinical Challenge |
title_fullStr | Stress Urinary Incontinence: An Unsolved Clinical Challenge |
title_full_unstemmed | Stress Urinary Incontinence: An Unsolved Clinical Challenge |
title_short | Stress Urinary Incontinence: An Unsolved Clinical Challenge |
title_sort | stress urinary incontinence: an unsolved clinical challenge |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525672/ https://www.ncbi.nlm.nih.gov/pubmed/37760927 http://dx.doi.org/10.3390/biomedicines11092486 |
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