Cargando…

Stress Urinary Incontinence: An Unsolved Clinical Challenge

Stress urinary incontinence is still a frequent problem for women and men, which leads to pronounced impairment of the quality of life and withdrawal from the social environment. Modern diagnostics and therapy improved the situation for individuals affected. But there are still limits, including the...

Descripción completa

Detalles Bibliográficos
Autores principales: Harland, Niklas, Walz, Simon, Eberli, Daniel, Schmid, Florian A., Aicher, Wilhelm K., Stenzl, Arnulf, Amend, Bastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525672/
https://www.ncbi.nlm.nih.gov/pubmed/37760927
http://dx.doi.org/10.3390/biomedicines11092486
_version_ 1785110840507105280
author Harland, Niklas
Walz, Simon
Eberli, Daniel
Schmid, Florian A.
Aicher, Wilhelm K.
Stenzl, Arnulf
Amend, Bastian
author_facet Harland, Niklas
Walz, Simon
Eberli, Daniel
Schmid, Florian A.
Aicher, Wilhelm K.
Stenzl, Arnulf
Amend, Bastian
author_sort Harland, Niklas
collection PubMed
description Stress urinary incontinence is still a frequent problem for women and men, which leads to pronounced impairment of the quality of life and withdrawal from the social environment. Modern diagnostics and therapy improved the situation for individuals affected. But there are still limits, including the correct diagnosis of incontinence and its pathophysiology, as well as the therapeutic algorithms. In most cases, patients are treated with a first-line regimen of drugs, possibly in combination with specific exercises and electrophysiological stimulation. When conservative options are exhausted, minimally invasive surgical therapies are indicated. However, standard surgeries, especially the application of implants, do not pursue any causal therapy. Non-absorbable meshes and ligaments have fallen into disrepute due to complications. In numerous countries, classic techniques such as colposuspension have been revived to avoid implants. Except for tapes in the treatment of stress urinary incontinence in women, the literature on randomized controlled studies is insufficient. This review provides an update on pharmacological and surgical treatment options for stress urinary incontinence; it highlights limitations and formulates wishes for the future from a clinical perspective.
format Online
Article
Text
id pubmed-10525672
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-105256722023-09-28 Stress Urinary Incontinence: An Unsolved Clinical Challenge Harland, Niklas Walz, Simon Eberli, Daniel Schmid, Florian A. Aicher, Wilhelm K. Stenzl, Arnulf Amend, Bastian Biomedicines Review Stress urinary incontinence is still a frequent problem for women and men, which leads to pronounced impairment of the quality of life and withdrawal from the social environment. Modern diagnostics and therapy improved the situation for individuals affected. But there are still limits, including the correct diagnosis of incontinence and its pathophysiology, as well as the therapeutic algorithms. In most cases, patients are treated with a first-line regimen of drugs, possibly in combination with specific exercises and electrophysiological stimulation. When conservative options are exhausted, minimally invasive surgical therapies are indicated. However, standard surgeries, especially the application of implants, do not pursue any causal therapy. Non-absorbable meshes and ligaments have fallen into disrepute due to complications. In numerous countries, classic techniques such as colposuspension have been revived to avoid implants. Except for tapes in the treatment of stress urinary incontinence in women, the literature on randomized controlled studies is insufficient. This review provides an update on pharmacological and surgical treatment options for stress urinary incontinence; it highlights limitations and formulates wishes for the future from a clinical perspective. MDPI 2023-09-07 /pmc/articles/PMC10525672/ /pubmed/37760927 http://dx.doi.org/10.3390/biomedicines11092486 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Harland, Niklas
Walz, Simon
Eberli, Daniel
Schmid, Florian A.
Aicher, Wilhelm K.
Stenzl, Arnulf
Amend, Bastian
Stress Urinary Incontinence: An Unsolved Clinical Challenge
title Stress Urinary Incontinence: An Unsolved Clinical Challenge
title_full Stress Urinary Incontinence: An Unsolved Clinical Challenge
title_fullStr Stress Urinary Incontinence: An Unsolved Clinical Challenge
title_full_unstemmed Stress Urinary Incontinence: An Unsolved Clinical Challenge
title_short Stress Urinary Incontinence: An Unsolved Clinical Challenge
title_sort stress urinary incontinence: an unsolved clinical challenge
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525672/
https://www.ncbi.nlm.nih.gov/pubmed/37760927
http://dx.doi.org/10.3390/biomedicines11092486
work_keys_str_mv AT harlandniklas stressurinaryincontinenceanunsolvedclinicalchallenge
AT walzsimon stressurinaryincontinenceanunsolvedclinicalchallenge
AT eberlidaniel stressurinaryincontinenceanunsolvedclinicalchallenge
AT schmidfloriana stressurinaryincontinenceanunsolvedclinicalchallenge
AT aicherwilhelmk stressurinaryincontinenceanunsolvedclinicalchallenge
AT stenzlarnulf stressurinaryincontinenceanunsolvedclinicalchallenge
AT amendbastian stressurinaryincontinenceanunsolvedclinicalchallenge