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Olfactory Bulbectomy Model of Depression Lowers Responding for Food in Male and Female Rats: The Modulating Role of Caloric Restriction and Response Requirement

Depression is a psychiatric disorder characterized by a marked decrease in reward sensitivity. By using the olfactory bulbectomy (OBX) model of depression, it was shown that OBX rats display enhanced drug-taking and seeking behaviors in a self-administration paradigm than sham-operated (SHAM) contro...

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Detalles Bibliográficos
Autores principales: Fattore, Liana, Amchova, Petra, Fadda, Paola, Ruda-Kucerova, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525806/
https://www.ncbi.nlm.nih.gov/pubmed/37760922
http://dx.doi.org/10.3390/biomedicines11092481