Global and Conditional Disruption of the Igf-I Gene in Osteoblasts and/or Chondrocytes Unveils Epiphyseal and Metaphyseal Bone-Specific Effects of IGF-I in Bone

SIMPLE SUMMARY: To investigate the relative importance of IGF-I expression in various types of bone cells for endochondral ossification, we examined the trabecular bone phenotypes at the distal femoral epiphysis and the secondary spongiosa of male mice with a global deletion of the Igf-I gene, as we...

Descripción completa

Detalles Bibliográficos
Autores principales: Xing, Weirong, Kesavan, Chandrasekhar, Pourteymoor, Sheila, Mohan, Subburaman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525837/
https://www.ncbi.nlm.nih.gov/pubmed/37759627
http://dx.doi.org/10.3390/biology12091228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525837/
https://www.ncbi.nlm.nih.gov/pubmed/37759627
http://dx.doi.org/10.3390/biology12091228

Ejemplares similares