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Global and Conditional Disruption of the Igf-I Gene in Osteoblasts and/or Chondrocytes Unveils Epiphyseal and Metaphyseal Bone-Specific Effects of IGF-I in Bone

SIMPLE SUMMARY: To investigate the relative importance of IGF-I expression in various types of bone cells for endochondral ossification, we examined the trabecular bone phenotypes at the distal femoral epiphysis and the secondary spongiosa of male mice with a global deletion of the Igf-I gene, as we...

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Detalles Bibliográficos
Autores principales:	Xing, Weirong, Kesavan, Chandrasekhar, Pourteymoor, Sheila, Mohan, Subburaman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525837/ https://www.ncbi.nlm.nih.gov/pubmed/37759627 http://dx.doi.org/10.3390/biology12091228

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