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Continuous Fentanyl Infusion in Newborns with Hypoxic–Ischemic Encephalopathy Treated with Therapeutic Hypothermia: Background, Aims, and Study Protocol for Time-Concentration Profiles

Therapeutic hypothermia (TH) is the standard of care for newborns with moderate to severe hypoxic–ischemic encephalopathy (HIE). Discomfort and pain during treatment are common and may affect the therapeutic efficacy of TH. Opioid sedation and analgesia (SA) are generally used in clinical practice,...

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Detalles Bibliográficos
Autores principales: Lugli, Licia, Garetti, Elisabetta, Goffredo, Bianca Maria, Candia, Francesco, Crestani, Sara, Spada, Caterina, Guidotti, Isotta, Bedetti, Luca, Miselli, Francesca, Della Casa, Elisa Muttini, Roversi, Maria Federica, Simeoli, Raffaele, Cairoli, Sara, Merazzi, Daniele, Lago, Paola, Iughetti, Lorenzo, Berardi, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525845/
https://www.ncbi.nlm.nih.gov/pubmed/37760835
http://dx.doi.org/10.3390/biomedicines11092395