Cargando…
Isolation and Biological Evaluation of Alfa-Mangostin as Potential Therapeutic Agents against Liver Fibrosis
The increased proliferation and activation of hepatic stellate cells (HSCs) are associated with liver fibrosis development. To date, there are no FDA-approved drugs for the treatment of liver cirrhosis. Augmentation of HSCs apoptosis is one of the resolutions for liver fibrosis. In this study, we ex...
Autores principales: | Liao, Yi-Jen, Lee, Chun-Ya, Twu, Yuh-Ching, Suk, Fat-Moon, Lai, Tzu-Chieh, Chang, Ya-Ching, Lai, Yi-Cheng, Yuan, Jing-Wei, Jhuang, Hong-Ming, Jian, Huei-Ruei, Huang, Li-Chia, Chen, Kuang-Po, Hsu, Ming-Hua |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526009/ https://www.ncbi.nlm.nih.gov/pubmed/37760177 http://dx.doi.org/10.3390/bioengineering10091075 |
Ejemplares similares
-
Long-Term Exposure to Low-Dose Di-(2-ethylhexyl) Phthalate Impairs Cholesterol Metabolism in Hepatic Stellate Cells and Exacerbates Liver Librosis
por: Lee, Chun-Ya, et al.
Publicado: (2020) -
Antifibrotic Effects of a Barbituric Acid Derivative on Liver Fibrosis by Blocking the NF-κB Signaling Pathway in Hepatic Stellate Cells
por: Wang, Yuan-Hsi, et al.
Publicado: (2020) -
Clinical Utility of Elosulfase Alfa in the Treatment of Morquio A Syndrome
por: Lee, Chung-Lin, et al.
Publicado: (2022) -
Niemann-Pick Type C2 Protein Regulates Free Cholesterol Accumulation and Influences Hepatic Stellate Cell Proliferation and Mitochondrial Respiration Function
por: Wang, Yuan-Hsi, et al.
Publicado: (2018) -
Glycine N-methyltransferase deficiency in female mice impairs insulin signaling and promotes gluconeogenesis by modulating the PI3K/Akt pathway in the liver
por: Liao, Yi-Jen, et al.
Publicado: (2016)