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Blockade of the SRC/STAT3/BCL-2 Signaling Axis Sustains the Cytotoxicity in Human Colorectal Cancer Cell Lines Induced by Dehydroxyhispolon Methyl Ether

Colorectal cancer (CRC) is the third most prevalent human cancer globally. 5-Fluorouracil (5-FU)-based systemic chemotherapy is the primary strategy for advanced CRC treatment, yet is limited by poor response rate. Deregulated activation of signal transducer and activator of transcription 3 (STAT3)...

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Detalles Bibliográficos
Autores principales:	Hsieh, Ya-Chu, Dai, Yuan-Chang, Cheng, Kur-Ta, Yang, Wei-Ting, Ramani, Modukuri V., Subbaraju, Gottumukkala V., Chen, Yi-Ju, Chang, Chia-Che
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526010/ https://www.ncbi.nlm.nih.gov/pubmed/37760971 http://dx.doi.org/10.3390/biomedicines11092530

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