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Change in Splenic Volume as a Surrogate Marker for Immunotherapy Response in Patients with Advanced Urothelial and Renal Cell Carcinoma—Evaluation of a Novel Approach of Fully Automated Artificial Intelligence Based Splenic Segmentation
Background: In the treatment of advanced urothelial (aUC) and renal cell carcinoma (aRCC), biomarkers such as PD-1 and PD-L1 are not robust prognostic markers for immunotherapy (IO) response. Previously, a significant association between IO and a change in splenic volume (SV) was described for sever...
Autores principales: | Duwe, Gregor, Müller, Lukas, Ruckes, Christian, Fischer, Nikita Dhruva, Frey, Lisa Johanna, Börner, Jan Hendrik, Rölz, Niklas, Haack, Maximilian, Sparwasser, Peter, Jorg, Tobias, Neumann, Christopher C. M., Tsaur, Igor, Höfner, Thomas, Haferkamp, Axel, Hahn, Felix, Mager, Rene, Brandt, Maximilian Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526098/ https://www.ncbi.nlm.nih.gov/pubmed/37760923 http://dx.doi.org/10.3390/biomedicines11092482 |
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