In Vitro and In Silico Investigation of BCI Anticancer Properties and Its Potential for Chemotherapy-Combined Treatments

SIMPLE SUMMARY: BCI is an allosteric inhibitor of DUSP6 phosphatase, which is a negative regulator of MAPK kinases involved in numerous cellular processes such as proliferation, differentiation, and survival. These studies were designed to test the anticancer potential of BCI in colorectal cancer (C...

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Detalles Bibliográficos
Autores principales: Marciniak, Beata, Kciuk, Mateusz, Mujwar, Somdutt, Sundaraj, Rajamanikandan, Bukowski, Karol, Gruszka, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526149/
https://www.ncbi.nlm.nih.gov/pubmed/37760412
http://dx.doi.org/10.3390/cancers15184442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526149/
https://www.ncbi.nlm.nih.gov/pubmed/37760412
http://dx.doi.org/10.3390/cancers15184442

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