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The Effect of SERCA Activation on Functional Characteristics and Signaling of Rat Soleus Muscle upon 7 Days of Unloading

Skeletal muscle abnormalities and atrophy during unloading are accompanied by the accumulation of excess calcium in the sarcoplasm. We hypothesized that calcium accumulation may occur, among other mechanisms, due to the inhibition of sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA) activity. Conseq...

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Detalles Bibliográficos
Autores principales: Sharlo, Kristina A., Lvova, Irina D., Tyganov, Sergey A., Zaripova, Ksenia A., Belova, Svetlana P., Kostrominova, Tatiana Y., Shenkman, Boris S., Nemirovskaya, Tatiana L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526198/
https://www.ncbi.nlm.nih.gov/pubmed/37759754
http://dx.doi.org/10.3390/biom13091354