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VprBP/DCAF1 Triggers Melanomagenic Gene Silencing through Histone H2A Phosphorylation

Vpr binding protein (VprBP), also known as DDB1- and CUL4-associated factor1 (DCAF1), is a recently identified atypical kinase and plays an important role in downregulating the transcription of tumor suppressor genes as well as increasing the risk for colon and prostate cancers. Melanoma is the most...

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Detalles Bibliográficos
Autores principales: Shin, Yonghwan, Kim, Sungmin, Liang, Gangning, Ulmer, Tobias S., An, Woojin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526264/
https://www.ncbi.nlm.nih.gov/pubmed/37760992
http://dx.doi.org/10.3390/biomedicines11092552