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VprBP/DCAF1 Triggers Melanomagenic Gene Silencing through Histone H2A Phosphorylation
Vpr binding protein (VprBP), also known as DDB1- and CUL4-associated factor1 (DCAF1), is a recently identified atypical kinase and plays an important role in downregulating the transcription of tumor suppressor genes as well as increasing the risk for colon and prostate cancers. Melanoma is the most...
Autores principales: | Shin, Yonghwan, Kim, Sungmin, Liang, Gangning, Ulmer, Tobias S., An, Woojin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526264/ https://www.ncbi.nlm.nih.gov/pubmed/37760992 http://dx.doi.org/10.3390/biomedicines11092552 |
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