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Thioredoxin Reductase and Organometallic Complexes: A Pivotal System to Tackle Multidrug Resistant Tumors?

SIMPLE SUMMARY: The identification of biological targets is an essential step in deciphering the mechanism of action of anticancer drugs. In this review, we chose to study the relationship between the inhibition of thioredoxin reductase (TrxR), a key enzyme in maintaining the redox balance of cells,...

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Detalles Bibliográficos
Autores principales: Salmain, Michèle, Gaschard, Marie, Baroud, Milad, Lepeltier, Elise, Jaouen, Gérard, Passirani, Catherine, Vessières, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526406/
https://www.ncbi.nlm.nih.gov/pubmed/37760418
http://dx.doi.org/10.3390/cancers15184448