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Analysis of Acute and Chronic Methamphetamine Treatment in Mice on Gdnf System Expression Reveals a Potential Mechanism of Schizophrenia Susceptibility

The increase in presynaptic striatal dopamine is the main dopaminergic abnormality in schizophrenia (SCZ). SCZ is primarily treated by modulating the activity of monoamine systems, with a focus on dopamine and serotonin receptors. Glial cell line-derived neurotrophic factor (GDNF) is a strong dopami...

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Detalles Bibliográficos
Autores principales: Casserly, Laoise, Garton, Daniel R., Montaño-Rodriguez, Ana, Andressoo, Jaan-Olle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526418/
https://www.ncbi.nlm.nih.gov/pubmed/37759827
http://dx.doi.org/10.3390/biom13091428