Heme Oxygenase-1 Inhibition Modulates Autophagy and Augments Arsenic Trioxide Cytotoxicity in Pancreatic Cancer Cells

Pancreatic ductal adenocarcinoma (PDAC) is the most prevalent form, accounting for more than 90% of all pancreatic malignancies. In a previous study, we found that hypoxia and chemotherapy induced expression of Heme Oxygenase-1 (HO-1) in PDAC cells and tissues. Arsenic trioxide (ATO) is the first-li...

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Detalles Bibliográficos
Autores principales: Ahmad, Iman M., Dafferner, Alicia J., Salloom, Ramia J., Abdalla, Maher Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526552/
https://www.ncbi.nlm.nih.gov/pubmed/37761021
http://dx.doi.org/10.3390/biomedicines11092580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526552/
https://www.ncbi.nlm.nih.gov/pubmed/37761021
http://dx.doi.org/10.3390/biomedicines11092580

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