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Targeting cullin neddylation for cancer and fibrotic diseases

Protein neddylation is a post-translational modification, and its best recognized substrates are cullin family proteins, which are the core component of Cullin-RING ligases (CRLs). Given that most neddylation pathway proteins are overactivated in different cancers and fibrotic diseases, targeting ne...

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Detalles Bibliográficos
Autores principales:	He, Zhang-Xu, Yang, Wei-guang, Zengyangzong, Dan, Gao, Ge, Zhang, Qian, Liu, Hong-Min, Zhao, Wen, Ma, Li-Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526667/ https://www.ncbi.nlm.nih.gov/pubmed/37771770 http://dx.doi.org/10.7150/thno.78876

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