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Amyloid-Beta Peptides Trigger Premature Functional and Gene Expression Alterations in Human-Induced Neurons

Alzheimer’s disease (AD) is the most prevalent cause of dementia in the elderly, characterized by the presence of amyloid-beta (Aβ) plaques, neurofibrillary tangles, neuroinflammation, synapse loss and neurodegeneration in the brain. The amyloid cascade hypothesis postulates that deposition of Aβ pe...

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Detalles Bibliográficos
Autores principales:	Melo de Farias, Ana Raquel, Pelletier, Alexandre, Iohan, Lukas Cruz Carvalho, Saha, Orthis, Bonnefond, Amélie, Amouyel, Philippe, Delahaye, Fabien, Lambert, Jean-Charles, Costa, Marcos R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526858/ https://www.ncbi.nlm.nih.gov/pubmed/37761004 http://dx.doi.org/10.3390/biomedicines11092564

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