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Modulation of Pro-Inflammatory IL-6 Trans-Signaling Axis by Splice Switching Oligonucleotides as a Therapeutic Modality in Inflammation

Interleukin-6 (IL-6) is a pleiotropic cytokine that plays a crucial role in maintaining normal homeostatic processes under the pathogenesis of various inflammatory and autoimmune diseases. This context-dependent effect from a cytokine is due to two distinctive forms of signaling: cis-signaling and t...

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Detalles Bibliográficos
Autores principales:	Gupta, Dhanu, Orehek, Sara, Turunen, Janne, O’Donovan, Liz, Gait, Michael J., El-Andaloussi, Samir, Wood, Matthew J. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10526877/ https://www.ncbi.nlm.nih.gov/pubmed/37759507 http://dx.doi.org/10.3390/cells12182285

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