A Lysine Residue at the C-Terminus of MHC Class I Ligands Correlates with Low C-Terminal Proteasomal Cleavage Probability

The majority of peptides presented by MHC class I result from proteasomal protein turnover. The specialized immunoproteasome, which is induced during inflammation, plays a major role in antigenic peptide generation. However, other cellular proteases can, either alone or together with the proteasome,...

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Detalles Bibliográficos
Autores principales: Schmalen, Adrian, Kammerl, Ilona E., Meiners, Silke, Noessner, Elfriede, Deeg, Cornelia A., Hauck, Stefanie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527444/
https://www.ncbi.nlm.nih.gov/pubmed/37759700
http://dx.doi.org/10.3390/biom13091300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527444/
https://www.ncbi.nlm.nih.gov/pubmed/37759700
http://dx.doi.org/10.3390/biom13091300

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