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A Lysine Residue at the C-Terminus of MHC Class I Ligands Correlates with Low C-Terminal Proteasomal Cleavage Probability
The majority of peptides presented by MHC class I result from proteasomal protein turnover. The specialized immunoproteasome, which is induced during inflammation, plays a major role in antigenic peptide generation. However, other cellular proteases can, either alone or together with the proteasome,...
Autores principales: | Schmalen, Adrian, Kammerl, Ilona E., Meiners, Silke, Noessner, Elfriede, Deeg, Cornelia A., Hauck, Stefanie M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527444/ https://www.ncbi.nlm.nih.gov/pubmed/37759700 http://dx.doi.org/10.3390/biom13091300 |
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