Pegylated Liposomal Alendronate Biodistribution, Immune Modulation, and Tumor Growth Inhibition in a Murine Melanoma Model

While tumor-associated macrophages (TAM) have pro-tumoral activity, the ablation of macrophages in cancer may be undesirable since they also have anti-tumoral functions, including T cell priming and activation against tumor antigens. Alendronate is a potent amino-bisphosphonate that modulates the fu...

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Detalles Bibliográficos
Autores principales: Islam, Md. Rakibul, Patel, Jalpa, Back, Patricia Ines, Shmeeda, Hilary, Kallem, Raja Reddy, Shudde, Claire, Markiewski, Maciej, Putnam, William C., Gabizon, Alberto A., La-Beck, Ninh M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527549/
https://www.ncbi.nlm.nih.gov/pubmed/37759709
http://dx.doi.org/10.3390/biom13091309

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