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Altered Epigenetic Marks and Gene Expression in Fetal Brain, and Postnatal Behavioural Disorders, Following Prenatal Exposure of Ogg1 Knockout Mice to Saline or Ethanol

Oxoguanine glycosylase 1 (OGG1) is widely known to repair the reactive oxygen species (ROS)-initiated DNA lesion 8-oxoguanine (8-oxoG), and more recently was shown to act as an epigenetic modifier. We have previously shown that saline-exposed Ogg1 −/− knockout progeny exhibited learning and memory d...

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Detalles Bibliográficos
Autores principales: Bhatia, Shama, Bodenstein, David, Cheng, Ashley P., Wells, Peter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527575/
https://www.ncbi.nlm.nih.gov/pubmed/37759530
http://dx.doi.org/10.3390/cells12182308