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Investigation of Tumor Heterogeneity Using Integrated Single-Cell RNA Sequence Analysis to Focus on Genes Related to Breast Cancer-, EMT-, CSC-, and Metastasis-Related Markers in Patients with HER2-Positive Breast Cancer

Human epidermal growth factor receptor 2 (HER2) protein, which is characterized by the amplification of ERBB2, is a molecular target for HER2-overexpressing breast cancer. Many targeted HER2 strategies have been well developed thus far. Furthermore, intratumoral heterogeneity in HER2 cases has been...

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Detalles Bibliográficos
Autores principales: Shiino, Sho, Tokura, Momoko, Nakayama, Jun, Yoshida, Masayuki, Suto, Akihiko, Yamamoto, Yusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527746/
https://www.ncbi.nlm.nih.gov/pubmed/37759508
http://dx.doi.org/10.3390/cells12182286