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Interactions between the DNA Damage Response and the Telomere Complex in Carcinogenesis: A Hypothesis
Contrary to what was once thought, direct cancer originating from normal stem cells seems to be extremely rare. This is consistent with a preneoplastic period of telomere length reduction/damage in committed cells that becomes stabilized in transformation. Multiple observations suggest that telomere...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527771/ https://www.ncbi.nlm.nih.gov/pubmed/37754262 http://dx.doi.org/10.3390/cimb45090478 |