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Ultrasound Doppler Findings in Fetal Vascular Malperfusion Due to Umbilical Cord Abnormalities: A Pilot Case Predictive for Cerebral Palsy

Fetal Vascular Malperfusion (FVM), a pathologic condition in the feto-placental circulation, is a chronic vaso-occlusive disorder in the umbilical venous blood flow. Microthrombi are caused by the umbilical cord’s blood flow deficiency in a congested umbilical vein, which also causes microvascular d...

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Autores principales: Saji, Shota, Hasegawa, Junichi, Koike, Junki, Takatsuki, Misato, Furuya, Natsumi, Suzuki, Nao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527923/
https://www.ncbi.nlm.nih.gov/pubmed/37761344
http://dx.doi.org/10.3390/diagnostics13182977
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author Saji, Shota
Hasegawa, Junichi
Koike, Junki
Takatsuki, Misato
Furuya, Natsumi
Suzuki, Nao
author_facet Saji, Shota
Hasegawa, Junichi
Koike, Junki
Takatsuki, Misato
Furuya, Natsumi
Suzuki, Nao
author_sort Saji, Shota
collection PubMed
description Fetal Vascular Malperfusion (FVM), a pathologic condition in the feto-placental circulation, is a chronic vaso-occlusive disorder in the umbilical venous blood flow. Microthrombi are caused by the umbilical cord’s blood flow deficiency in a congested umbilical vein, which also causes microvascular damage to fetal organs, especially the brain, resulting in cerebral palsy. Thrombo-occlusive events also adversely affect the upstream chorionic or stem vessels in the placenta, resulting in fetal growth restriction and fetal hypoxia. An umbilical cord structural anomaly or multiple entanglements may involve FVM. In the present report, we demonstrate a case of FVM caused by multiple umbilical cord abnormalities obtained from antenatal ultrasound Doppler findings, and we also discuss FVM, which is chronically associated with CP, comparing the ultrasonographic findings to the pathologic findings.
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spelling pubmed-105279232023-09-28 Ultrasound Doppler Findings in Fetal Vascular Malperfusion Due to Umbilical Cord Abnormalities: A Pilot Case Predictive for Cerebral Palsy Saji, Shota Hasegawa, Junichi Koike, Junki Takatsuki, Misato Furuya, Natsumi Suzuki, Nao Diagnostics (Basel) Interesting Images Fetal Vascular Malperfusion (FVM), a pathologic condition in the feto-placental circulation, is a chronic vaso-occlusive disorder in the umbilical venous blood flow. Microthrombi are caused by the umbilical cord’s blood flow deficiency in a congested umbilical vein, which also causes microvascular damage to fetal organs, especially the brain, resulting in cerebral palsy. Thrombo-occlusive events also adversely affect the upstream chorionic or stem vessels in the placenta, resulting in fetal growth restriction and fetal hypoxia. An umbilical cord structural anomaly or multiple entanglements may involve FVM. In the present report, we demonstrate a case of FVM caused by multiple umbilical cord abnormalities obtained from antenatal ultrasound Doppler findings, and we also discuss FVM, which is chronically associated with CP, comparing the ultrasonographic findings to the pathologic findings. MDPI 2023-09-18 /pmc/articles/PMC10527923/ /pubmed/37761344 http://dx.doi.org/10.3390/diagnostics13182977 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Interesting Images
Saji, Shota
Hasegawa, Junichi
Koike, Junki
Takatsuki, Misato
Furuya, Natsumi
Suzuki, Nao
Ultrasound Doppler Findings in Fetal Vascular Malperfusion Due to Umbilical Cord Abnormalities: A Pilot Case Predictive for Cerebral Palsy
title Ultrasound Doppler Findings in Fetal Vascular Malperfusion Due to Umbilical Cord Abnormalities: A Pilot Case Predictive for Cerebral Palsy
title_full Ultrasound Doppler Findings in Fetal Vascular Malperfusion Due to Umbilical Cord Abnormalities: A Pilot Case Predictive for Cerebral Palsy
title_fullStr Ultrasound Doppler Findings in Fetal Vascular Malperfusion Due to Umbilical Cord Abnormalities: A Pilot Case Predictive for Cerebral Palsy
title_full_unstemmed Ultrasound Doppler Findings in Fetal Vascular Malperfusion Due to Umbilical Cord Abnormalities: A Pilot Case Predictive for Cerebral Palsy
title_short Ultrasound Doppler Findings in Fetal Vascular Malperfusion Due to Umbilical Cord Abnormalities: A Pilot Case Predictive for Cerebral Palsy
title_sort ultrasound doppler findings in fetal vascular malperfusion due to umbilical cord abnormalities: a pilot case predictive for cerebral palsy
topic Interesting Images
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527923/
https://www.ncbi.nlm.nih.gov/pubmed/37761344
http://dx.doi.org/10.3390/diagnostics13182977
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