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Preoperative Embolization of Vertebral Metastasis: Comprehensive Review of the Literature

The aim of this review is to determine the safety and efficacy of pre-operative spinal metastases embolization procedures. Two reviewers independently conducted the literature search (on MEDLINE databases), including in the review of all the studies that used pre-operative TAE to treat spinal metast...

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Detalles Bibliográficos
Autores principales: Faiella, Eliodoro, Santucci, Domiziana, Vertulli, Daniele, Russo, Fabrizio, Vadalà, Gianluca, Papalia, Rocco, Beomonte Zobel, Bruno, Denaro, Vincenzo, Grasso, Rosario Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528004/
https://www.ncbi.nlm.nih.gov/pubmed/37754305
http://dx.doi.org/10.3390/diseases11030109
Descripción
Sumario:The aim of this review is to determine the safety and efficacy of pre-operative spinal metastases embolization procedures. Two reviewers independently conducted the literature search (on MEDLINE databases), including in the review of all the studies that used pre-operative TAE to treat spinal metastases. Twelve articles on pre-operative spinal metastases embolization were selected. Most of the studies demonstrated the low complication rate of pre-operative embolization. The most important study strength is that there are very few reviews in the literature with the setting on pre-operative vertebral metastases embolization. A limitation of the review is that the studies included were predominately retrospective case-control studies, increasing the risk of bias in the primary data. Plus, divergent surgical and embolization procedures were performed in the studies, causing a potential risk of bias in the pooled results. We can conclude that preoperative arterial embolization of vertebral metastases is a safe, well-tolerated technique that reduces surgical blood loss and facilitates surgical tumor resection.