Cargando…

In Silico Bioinformatics Analysis on the Role of Long Non-Coding RNAs as Drivers and Gatekeepers of Androgen-Independent Prostate Cancer Using LNCaP and PC-3 Cells

Prostate cancer (PCa) is the leading cancer in men globally. The association between PCa and long non-coding RNAs (lncRNAs) has been reported. Aberrantly expressed lncRNAs have been documented in each of the cancer “hallmarks”. Androgen signaling plays an important role in PCa progression. This stud...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mbeje, Mandisa, Kandhavelu, Jeyalakshmi, Penny, Clement, Kgoebane-Maseko, Mmamoletla, Dlamini, Zodwa, Marima, Rahaba
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528188/ https://www.ncbi.nlm.nih.gov/pubmed/37754243 http://dx.doi.org/10.3390/cimb45090459

Ejemplares similares

Prostate Cancer Disparities and Management in Southern Africa: Insights into Practices, Norms and Values
por: Marima, Rahaba, et al.
Publicado: (2022)

The Catastrophic HPV/HIV Dual Viral Oncogenomics in Concert with Dysregulated Alternative Splicing in Cervical Cancer
por: Marima, Rahaba, et al.
Publicado: (2021)

Role of Precision Oncology in Type II Endometrial and Prostate Cancers in the African Population: Global Cancer Genomics Disparities
por: Marima, Rahaba, et al.
Publicado: (2022)

Efavirenz induces DNA damage response pathway in lung cancer
por: Marima, Rahaba, et al.
Publicado: (2020)

Efavirenz and Lopinavir/Ritonavir Alter Cell Cycle Regulation in Lung Cancer
por: Marima, Rahaba, et al.
Publicado: (2020)

The profiling, identification, quantification and analysis of differentially expressed genes (DEGs) in response to drug treatment in lung cancer
por: Marima, Rahaba, et al.
Publicado: (2021)

Role and Merits of Green Based Nanocarriers in Cancer Treatment
por: Elbagory, Abdulrahman M., et al.
Publicado: (2021)

Alteration of Androgen Receptor Protein Stability by Triptolide in LNCaP Cells
por: Li, Wei, et al.
Publicado: (2018)

Whole-Genome Sequence of the Metastatic PC3 and LNCaP Human Prostate Cancer Cell Lines
por: Seim, Inge, et al.
Publicado: (2017)

Artificial intelligence (AI) and big data in cancer and precision oncology
por: Dlamini, Zodwa, et al.
Publicado: (2020)

Androgen-independent LNCaP cells are a subline of LNCaP cells with a more aggressive phenotype and androgen suppresses their growth by inducing cell cycle arrest at the G1 phase
por: Yu, Pan, et al.
Publicado: (2017)

Androgen upregulates the palmitoylation of eIF3L in human prostate LNCaP cells
por: Cui, Luwei, et al.
Publicado: (2019)

HIV-Associated Cancer Biomarkers: A Requirement for Early Diagnosis
por: Dlamini, Zodwa, et al.
Publicado: (2021)

ADAMTS1 alters blood vessel morphology and TSP1 levels in LNCaP and LNCaP-19 prostate tumors
por: Gustavsson, Heléne, et al.
Publicado: (2010)

Synthetic androgens suppress the transformed phenotype in the human prostate carcinoma cell line LNCaP.
por: Wolf, D. A., et al.
Publicado: (1991)

Effect of curcumin on the interaction between androgen receptor and Wnt/β-catenin in LNCaP xenografts
por: Hong, Jeong Hee, et al.
Publicado: (2015)

Chronic IL-1 exposure drives LNCaP cells to evolve androgen and AR independence
por: Dahl, Haley C., et al.
Publicado: (2020)

MicroRNA-652 induces NED in LNCaP and EMT in PC3 prostate cancer cells
por: Nam, Robert K., et al.
Publicado: (2018)

Dissecting Microbiome-Derived SCFAs in Prostate Cancer: Analyzing Gut Microbiota, Racial Disparities, and Epigenetic Mechanisms
por: Miya, Thabiso Victor, et al.
Publicado: (2023)

Role of Androgen Receptor in Progression of LNCaP Prostate Cancer Cells from G(1) to S Phase
por: Murthy, Shalini, et al.
Publicado: (2013)

Cholesterol Homeostasis in Two Commonly Used Human Prostate Cancer Cell-Lines, LNCaP and PC-3
por: Krycer, James Robert, et al.
Publicado: (2009)

Effectiveness of the Histone Deacetylase Inhibitor (S)-2 against LNCaP and PC3 Human Prostate Cancer Cells
por: Laurenzana, Anna, et al.
Publicado: (2013)

Effect of silencing the T-Box transcription factor TBX2 in prostate cancer PC3 and LNCaP cells
por: Du, Wen-Liang, et al.
Publicado: (2017)

Enhanced sensitivity to androgen withdrawal due to overexpression of interleukin-6 in androgen-dependent human prostate cancer LNCaP cells
por: Terakawa, T, et al.
Publicado: (2009)

CRISPR/Cas9 targeting of the androgen receptor suppresses the growth of LNCaP human prostate cancer cells
por: Wei, Chaogang, et al.
Publicado: (2018)

Ophiopogonin D' induces RIPK1-dependent necroptosis in androgen-dependent LNCaP prostate cancer cells
por: Lu, Zongliang, et al.
Publicado: (2019)

Efficacy of PACE4 pharmacotherapy in JHU-LNCaP-SM preclinical model of androgen independent prostate cancer
por: Mekdad, Nawel, et al.
Publicado: (2022)

Apogossypolone inhibits the proliferation of LNCaP cells in vitro and in vivo
por: ZHANG, XIANQING, et al.
Publicado: (2014)

Apogossypolone inhibits the proliferation of LNCaP cells in vitro and in vivo
por: Zhang, Xianqing, et al.
Publicado: (2018)

Viral Encoded miRNAs in Tumorigenesis: Theranostic Opportunities in Precision Oncology
por: Hull, Rodney, et al.
Publicado: (2022)

Competing Endogenous RNA (ceRNA) Networks and Splicing Switches in Cervical Cancer: HPV Oncogenesis, Clinical Significance and Therapeutic Opportunities
por: Basera, Afra, et al.
Publicado: (2022)

Optimal timing and dosage of chemotherapy as a combined treatment with androgen withdrawal in the human prostate LNCaP tumour model
por: Miyake, H, et al.
Publicado: (2001)

Heat shock protein 70 inhibitors suppress androgen receptor expression in LNCaP95 prostate cancer cells
por: Kita, Kazuaki, et al.
Publicado: (2017)

Cucurbitacin-B instigates intrinsic apoptosis and modulates Notch signaling in androgen-dependent prostate cancer LNCaP cells
por: Alafnan, Ahmed, et al.
Publicado: (2023)

The Effects of Lycopene on the Methylation of the GSTP1 Promoter and Global Methylation in Prostatic Cancer Cell Lines PC3 and LNCaP
por: Fu, Li-Juan, et al.
Publicado: (2014)

Sodium bicarbonate transporter NBCe1 regulates proliferation and viability of human prostate cancer cells LNCaP and PC3
por: Li, Jun Ming, et al.
Publicado: (2021)

Osteopontin-c mediates the upregulation of androgen responsive genes in LNCaP cells through PI3K/Akt and androgen receptor signaling
por: TILLI, TATIANA MARTINS, et al.
Publicado: (2015)

Calcitriol and TO-901317 Interact in Human Prostate Cancer LNCaP Cells
por: Wang, Jing-Huan, et al.
Publicado: (2008)

URG11 promotes proliferation and induced apoptosis of LNCaP cells
por: Sun, Chenmin, et al.
Publicado: (2019)

HOXB13 promotes androgen independent growth of LNCaP prostate cancer cells by the activation of E2F signaling
por: Kim, Young-Rang, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_7pudrn17br7fjqe1hpuubvh841