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Implementing AI Models for Prognostic Predictions in High-Risk Burn Patients

Background and Objectives: Burn injuries range from minor medical issues to severe, life-threatening conditions. The severity and location of the burn dictate its treatment; while minor burns might be treatable at home, severe burns necessitate medical intervention, sometimes in specialized burn cen...

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Autores principales: Yeh, Chin-Choon, Lin, Yu-San, Chen, Chun-Chia, Liu, Chung-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528558/
https://www.ncbi.nlm.nih.gov/pubmed/37761351
http://dx.doi.org/10.3390/diagnostics13182984
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author Yeh, Chin-Choon
Lin, Yu-San
Chen, Chun-Chia
Liu, Chung-Feng
author_facet Yeh, Chin-Choon
Lin, Yu-San
Chen, Chun-Chia
Liu, Chung-Feng
author_sort Yeh, Chin-Choon
collection PubMed
description Background and Objectives: Burn injuries range from minor medical issues to severe, life-threatening conditions. The severity and location of the burn dictate its treatment; while minor burns might be treatable at home, severe burns necessitate medical intervention, sometimes in specialized burn centers with extended follow-up care. This study aims to leverage artificial intelligence (AI)/machine learning (ML) to forecast potential adverse effects in burn patients. Methods: This retrospective analysis considered burn patients admitted to Chi Mei Medical Center from 2010 to 2019. The study employed 14 features, comprising supplementary information like prior comorbidities and laboratory results, for building models for predicting graft surgery, a prolonged hospital stay, and overall adverse effects. Overall, 70% of the data set trained the AI models, with the remaining 30% reserved for testing. Three ML algorithms of random forest, LightGBM, and logistic regression were employed with evaluation metrics of accuracy, sensitivity, specificity, and the area under the receiver operating characteristic curve (AUC). Results: In this research, out of 224 patients assessed, the random forest model yielded the highest AUC for predictions related to prolonged hospital stays (>14 days) at 81.1%, followed by the XGBoost (79.9%) and LightGBM (79.5%) models. Besides, the random forest model of the need for a skin graft showed the highest AUC (78.8%), while the random forest model and XGBoost model of the occurrence of adverse complications both demonstrated the highest AUC (87.2%) as well. Based on the best models with the highest AUC values, an AI prediction system is designed and integrated into hospital information systems to assist physicians in the decision-making process. Conclusions: AI techniques showcased exceptional capabilities for predicting a prolonged hospital stay, the need for a skin graft, and the occurrence of overall adverse complications for burn patients. The insights from our study fuel optimism for the inception of a novel predictive model that can seamlessly meld with hospital information systems, enhancing clinical decisions and bolstering physician–patient dialogues.
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spelling pubmed-105285582023-09-28 Implementing AI Models for Prognostic Predictions in High-Risk Burn Patients Yeh, Chin-Choon Lin, Yu-San Chen, Chun-Chia Liu, Chung-Feng Diagnostics (Basel) Article Background and Objectives: Burn injuries range from minor medical issues to severe, life-threatening conditions. The severity and location of the burn dictate its treatment; while minor burns might be treatable at home, severe burns necessitate medical intervention, sometimes in specialized burn centers with extended follow-up care. This study aims to leverage artificial intelligence (AI)/machine learning (ML) to forecast potential adverse effects in burn patients. Methods: This retrospective analysis considered burn patients admitted to Chi Mei Medical Center from 2010 to 2019. The study employed 14 features, comprising supplementary information like prior comorbidities and laboratory results, for building models for predicting graft surgery, a prolonged hospital stay, and overall adverse effects. Overall, 70% of the data set trained the AI models, with the remaining 30% reserved for testing. Three ML algorithms of random forest, LightGBM, and logistic regression were employed with evaluation metrics of accuracy, sensitivity, specificity, and the area under the receiver operating characteristic curve (AUC). Results: In this research, out of 224 patients assessed, the random forest model yielded the highest AUC for predictions related to prolonged hospital stays (>14 days) at 81.1%, followed by the XGBoost (79.9%) and LightGBM (79.5%) models. Besides, the random forest model of the need for a skin graft showed the highest AUC (78.8%), while the random forest model and XGBoost model of the occurrence of adverse complications both demonstrated the highest AUC (87.2%) as well. Based on the best models with the highest AUC values, an AI prediction system is designed and integrated into hospital information systems to assist physicians in the decision-making process. Conclusions: AI techniques showcased exceptional capabilities for predicting a prolonged hospital stay, the need for a skin graft, and the occurrence of overall adverse complications for burn patients. The insights from our study fuel optimism for the inception of a novel predictive model that can seamlessly meld with hospital information systems, enhancing clinical decisions and bolstering physician–patient dialogues. MDPI 2023-09-18 /pmc/articles/PMC10528558/ /pubmed/37761351 http://dx.doi.org/10.3390/diagnostics13182984 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Yeh, Chin-Choon
Lin, Yu-San
Chen, Chun-Chia
Liu, Chung-Feng
Implementing AI Models for Prognostic Predictions in High-Risk Burn Patients
title Implementing AI Models for Prognostic Predictions in High-Risk Burn Patients
title_full Implementing AI Models for Prognostic Predictions in High-Risk Burn Patients
title_fullStr Implementing AI Models for Prognostic Predictions in High-Risk Burn Patients
title_full_unstemmed Implementing AI Models for Prognostic Predictions in High-Risk Burn Patients
title_short Implementing AI Models for Prognostic Predictions in High-Risk Burn Patients
title_sort implementing ai models for prognostic predictions in high-risk burn patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528558/
https://www.ncbi.nlm.nih.gov/pubmed/37761351
http://dx.doi.org/10.3390/diagnostics13182984
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