IGFBPL1 is a master driver of microglia homeostasis and resolution of neuroinflammation in glaucoma and brain tauopathy

Microglia shift toward an inflammatory phenotype during aging that is thought to exacerbate age-related neurodegeneration. The molecular and cellular signals that resolve neuroinflammation post-injury are largely undefined. Here, we exploit systems genetics methods based on the extended BXD murine r...

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Detalles Bibliográficos
Autores principales: Pan, Li, Cho, Kin-Sang, Wei, Xin, Xu, Fuyi, Lennikov, Anton, Hu, Guangan, Tang, Jing, Guo, Shuai, Chen, Julie, Kriukov, Emil, Kyle, Robert, Elzaridi, Farris, Jiang, Shuhong, Dromel, Pierre A., Young, Michael, Baranov, Petr, Chi-Wai, Do, Williams, Robert W., Chen, Jianzhu, Lu, Lu, Chen, Dong Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528709/
https://www.ncbi.nlm.nih.gov/pubmed/37527036
http://dx.doi.org/10.1016/j.celrep.2023.112889

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