Cargando…

Airway stem cell reconstitution by the transplantation of primary or pluripotent stem cell-derived basal cells

Life-long reconstitution of a tissue’s resident stem cell compartment with engrafted cells has the potential to durably replenish organ function. Here, we demonstrate the engraftment of the airway epithelial stem cell compartment via intra-airway transplantation of mouse or human primary and pluripo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ma, Liang, Thapa, Bibek R., Le Suer, Jake A., Tilston-Lünel, Andrew, Herriges, Michael J., Berical, Andrew, Beermann, Mary Lou, Wang, Feiya, Bawa, Pushpinder S., Kohn, Anat, Ysasi, Alexandra B., Kiyokawa, Hirofumi, Matte, Taylor M., Randell, Scott H., Varelas, Xaralabos, Hawkins, Finn J., Kotton, Darrell N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528754/ https://www.ncbi.nlm.nih.gov/pubmed/37625411 http://dx.doi.org/10.1016/j.stem.2023.07.014

Ejemplares similares

Generation of human alveolar epithelial type I cells from pluripotent stem cells
por: Burgess, Claire L, et al.
Publicado: (2023)

Directed differentiation of mouse pluripotent stem cells into functional lung-specific mesenchyme
por: Alber, Andrea B., et al.
Publicado: (2023)

De Novo Generation of Pulmonary Ionocytes from Normal and Cystic Fibrosis Human Induced Pluripotent Stem Cells
por: Wang, Ruobing, et al.
Publicado: (2023)

Differentiation of human pluripotent stem cells into functional airway basal stem cells
por: Suzuki, Shingo, et al.
Publicado: (2021)

Yap/Taz inhibit goblet cell fate to maintain lung epithelial homeostasis
por: Hicks-Berthet, Julia, et al.
Publicado: (2021)

Obesity-induced senescent macrophages activate a fibrotic transcriptional program in adipocyte progenitors
por: Rabhi, Nabil, et al.
Publicado: (2022)

Basal extrusion of single‐oncogenic mutant cells induces dome‐like structures with altered microenvironments
por: Shirai, Takanobu, et al.
Publicado: (2022)

Generation of mesenchyme free intestinal organoids from human induced pluripotent stem cells
por: Mithal, Aditya, et al.
Publicado: (2020)

Editorial: Progenitors and Stem Cells in Thyroid Development, Disease, and Regeneration
por: Kotton, Darrell N., et al.
Publicado: (2022)

Challenges Facing Airway Epithelial Cell-Based Therapy for Cystic Fibrosis
por: Berical, Andrew, et al.
Publicado: (2019)

scTOP: physics-inspired order parameters for cellular identification and visualization
por: Yampolskaya, Maria, et al.
Publicado: (2023)

Loss of G-Protein Pathway Suppressor 2 Promotes Tumor Growth Through Activation of AKT Signaling
por: Chan, Stefanie, et al.
Publicado: (2021)

2292: Implementation and dissemination of a unique training program in stem cell biology and regenerative medicine
por: Jones, Matthew, et al.
Publicado: (2018)

Gene expression alterations in salivary gland epithelia of Sjögren’s syndrome patients are associated with clinical and histopathological manifestations
por: Dela Cruz, Ariana, et al.
Publicado: (2021)

Convergence of YAP/TAZ, TEAD and TP63 activity is associated with bronchial premalignant severity and progression
por: Ning, Boting, et al.
Publicado: (2023)

The COPD GWAS gene ADGRG6 instructs function and injury response in human iPSC-derived type II alveolar epithelial cells
por: Werder, Rhiannon B., et al.
Publicado: (2023)

Inactivation of LATS1/2 drives luminal-basal plasticity to initiate basal-like mammary carcinomas
por: Kern, Joseph G., et al.
Publicado: (2022)

Derivation of Thyroid Follicular Cells From Pluripotent Stem Cells: Insights From Development and Implications for Regenerative Medicine
por: Posabella, Alberto, et al.
Publicado: (2021)

Stem cells and repair of lung injuries
por: Neuringer, Isabel P, et al.
Publicado: (2004)

Human iPSC-hepatocyte modeling of alpha-1 antitrypsin heterozygosity reveals metabolic dysregulation and cellular heterogeneity
por: Kaserman, Joseph E., et al.
Publicado: (2022)

Transcriptional Analysis of Fracture Healing and the Induction of Embryonic Stem Cell–Related Genes
por: Bais, Manish, et al.
Publicado: (2009)

Expression of Amyloidogenic Transthyretin Drives Hepatic Proteostasis Remodeling in an Induced Pluripotent Stem Cell Model of Systemic Amyloid Disease
por: Giadone, Richard M., et al.
Publicado: (2020)

Inactivation of the Hippo tumor suppressor pathway promotes melanoma
por: Vittoria, Marc A., et al.
Publicado: (2022)

Willing to Be Involved in Cancer
por: Gunn-Moore, Frank J., et al.
Publicado: (2016)

Residual Expression of Reprogramming Factors Affects the Transcriptional Program and Epigenetic Signatures of Induced Pluripotent Stem Cells
por: Sommer, Cesar A., et al.
Publicado: (2012)

Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease
por: Alysandratos, Konstantinos-Dionysios, et al.
Publicado: (2021)

De novo hematopoiesis from the fetal lung
por: Yeung, Anthony K., et al.
Publicado: (2023)

Human iPSC-derived alveolar and airway epithelial cells can be cultured at air-liquid interface and express SARS-CoV-2 host factors
por: Abo, Kristine M., et al.
Publicado: (2020)

Willin/FRMD6 Influences Mechanical Phenotype and Neuronal Differentiation in Mammalian Cells by Regulating ERK1/2 Activity
por: Kronenberg, Nils M., et al.
Publicado: (2020)

Induced Pluripotent Stem Cell Modeling of Multisystemic, Hereditary Transthyretin Amyloidosis
por: Leung, Amy, et al.
Publicado: (2013)

Recapitulating human cardio-pulmonary co-development using simultaneous multilineage differentiation of pluripotent stem cells
por: Ng, Wai Hoe, et al.
Publicado: (2022)

The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future
por: Basil, Maria C., et al.
Publicado: (2020)

Single-Cell Transcriptomic Profiling of Pluripotent Stem Cell-Derived SCGB3A2+ Airway Epithelium
por: McCauley, Katherine B., et al.
Publicado: (2018)

A Highly Phenotyped Open Access Repository of Alpha-1 Antitrypsin Deficiency Pluripotent Stem Cells
por: Kaserman, Joseph E., et al.
Publicado: (2020)

The in vivo genetic program of murine primordial lung epithelial progenitors
por: Ikonomou, Laertis, et al.
Publicado: (2020)

SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response
por: Huang, Jessie, et al.
Publicado: (2020)

Culture impact on the transcriptomic programs of primary and iPSC-derived human alveolar type 2 cells
por: Alysandratos, Konstantinos-Dionysios, et al.
Publicado: (2023)

EP300 knockdown reduces cancer stem cell phenotype, tumor growth and metastasis in triple negative breast cancer
por: Ring, Alexander, et al.
Publicado: (2020)

Yap suppresses T-cell function and infiltration in the tumor microenvironment
por: Stampouloglou, Eleni, et al.
Publicado: (2020)

Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics
por: Terrenoire, Cecile, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_4li5per6ghj5ne0qemqvlkv99j