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Modified Vaginal Mesh Procedure with DynaMesh(®)-PR4 for the Treatment of Anterior/Apical Vaginal Prolapse

(1) Background: Treating female pelvic organ prolapse (POP) is challenging. Surgical meshes have been used in transvaginal surgeries since the 1990s, but complications such as mesh exposure and infection have been reported. Polyvinylidene fluoride (PVDF) mesh, known for its stability and non-reactiv...

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Autores principales: Lin, Chia-Ju, Liu, Chih-Ku, Hsieh, Hsiao-Yun, Chen, Ming-Jer, Tsai, Ching-Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528822/
https://www.ncbi.nlm.nih.gov/pubmed/37761358
http://dx.doi.org/10.3390/diagnostics13182991
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author Lin, Chia-Ju
Liu, Chih-Ku
Hsieh, Hsiao-Yun
Chen, Ming-Jer
Tsai, Ching-Pei
author_facet Lin, Chia-Ju
Liu, Chih-Ku
Hsieh, Hsiao-Yun
Chen, Ming-Jer
Tsai, Ching-Pei
author_sort Lin, Chia-Ju
collection PubMed
description (1) Background: Treating female pelvic organ prolapse (POP) is challenging. Surgical meshes have been used in transvaginal surgeries since the 1990s, but complications such as mesh exposure and infection have been reported. Polyvinylidene fluoride (PVDF) mesh, known for its stability and non-reactive properties, has shown promise in urogynecological surgeries. (2) Methods: A retrospective analysis was conducted on 27 patients who underwent a modified PVDF vaginal mesh repair procedure using DynaMesh(®)-PR4 and combined trans-obturator and sacrospinous fixation techniques. Additional surgeries were performed as needed. (3) Results: The mean operation time was 56.7 min, and the mean blood loss was 66.7 mL. The average hospitalization period was 4.2 days with Foley catheter removal after 2 days. Patients experienced lower pain scores from the day of the operation to the following day. Postoperative follow-up revealed that 85.2% of patients achieved anatomic success, with 14.8% experiencing recurrent stage II cystocele. No recurrence of apical prolapse was observed. Complications were rare, with one case (3.7%) of asymptomatic mesh protrusion. (4) Conclusions: The modified vaginal mesh procedure using DynaMesh(®)-PR4 showed favorable outcomes with a short operation time, low recurrence rate, rare complications, and improved functional outcomes. This surgical option could be considered for anterior and apical pelvic organ prolapse in women.
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spelling pubmed-105288222023-09-28 Modified Vaginal Mesh Procedure with DynaMesh(®)-PR4 for the Treatment of Anterior/Apical Vaginal Prolapse Lin, Chia-Ju Liu, Chih-Ku Hsieh, Hsiao-Yun Chen, Ming-Jer Tsai, Ching-Pei Diagnostics (Basel) Article (1) Background: Treating female pelvic organ prolapse (POP) is challenging. Surgical meshes have been used in transvaginal surgeries since the 1990s, but complications such as mesh exposure and infection have been reported. Polyvinylidene fluoride (PVDF) mesh, known for its stability and non-reactive properties, has shown promise in urogynecological surgeries. (2) Methods: A retrospective analysis was conducted on 27 patients who underwent a modified PVDF vaginal mesh repair procedure using DynaMesh(®)-PR4 and combined trans-obturator and sacrospinous fixation techniques. Additional surgeries were performed as needed. (3) Results: The mean operation time was 56.7 min, and the mean blood loss was 66.7 mL. The average hospitalization period was 4.2 days with Foley catheter removal after 2 days. Patients experienced lower pain scores from the day of the operation to the following day. Postoperative follow-up revealed that 85.2% of patients achieved anatomic success, with 14.8% experiencing recurrent stage II cystocele. No recurrence of apical prolapse was observed. Complications were rare, with one case (3.7%) of asymptomatic mesh protrusion. (4) Conclusions: The modified vaginal mesh procedure using DynaMesh(®)-PR4 showed favorable outcomes with a short operation time, low recurrence rate, rare complications, and improved functional outcomes. This surgical option could be considered for anterior and apical pelvic organ prolapse in women. MDPI 2023-09-18 /pmc/articles/PMC10528822/ /pubmed/37761358 http://dx.doi.org/10.3390/diagnostics13182991 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lin, Chia-Ju
Liu, Chih-Ku
Hsieh, Hsiao-Yun
Chen, Ming-Jer
Tsai, Ching-Pei
Modified Vaginal Mesh Procedure with DynaMesh(®)-PR4 for the Treatment of Anterior/Apical Vaginal Prolapse
title Modified Vaginal Mesh Procedure with DynaMesh(®)-PR4 for the Treatment of Anterior/Apical Vaginal Prolapse
title_full Modified Vaginal Mesh Procedure with DynaMesh(®)-PR4 for the Treatment of Anterior/Apical Vaginal Prolapse
title_fullStr Modified Vaginal Mesh Procedure with DynaMesh(®)-PR4 for the Treatment of Anterior/Apical Vaginal Prolapse
title_full_unstemmed Modified Vaginal Mesh Procedure with DynaMesh(®)-PR4 for the Treatment of Anterior/Apical Vaginal Prolapse
title_short Modified Vaginal Mesh Procedure with DynaMesh(®)-PR4 for the Treatment of Anterior/Apical Vaginal Prolapse
title_sort modified vaginal mesh procedure with dynamesh(®)-pr4 for the treatment of anterior/apical vaginal prolapse
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528822/
https://www.ncbi.nlm.nih.gov/pubmed/37761358
http://dx.doi.org/10.3390/diagnostics13182991
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