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A case report of the treatment and care of decubitus ulcers in macaques with spinal cord injury

Decubitus ulcers are a common spinal cord injury (SCI) complication that puts patients' lives in danger and has emerged as a more prevalent issue in modern clinical rehabilitation and care. Decubitus ulcers in humans can currently be treated in a number of different ways, but there are fewer st...

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Autores principales: Niu, Yong‐Min, Qin, Hao‐Yue, Liu, Jin‐Xiang, Li, Xin‐Yi, Wang, An‐Su, Sun, Ling‐Xia, Huang, Ni‐Jiao, Yang, Chang‐Wei, Cao, Yu, Bai, Tao, Lan, Yang, Liu, Sheng, Yuan, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528975/
https://www.ncbi.nlm.nih.gov/pubmed/37786554
http://dx.doi.org/10.1002/ibra.12105
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author Niu, Yong‐Min
Qin, Hao‐Yue
Liu, Jin‐Xiang
Li, Xin‐Yi
Wang, An‐Su
Sun, Ling‐Xia
Huang, Ni‐Jiao
Yang, Chang‐Wei
Cao, Yu
Bai, Tao
Lan, Yang
Liu, Sheng
Yuan, Hao
author_facet Niu, Yong‐Min
Qin, Hao‐Yue
Liu, Jin‐Xiang
Li, Xin‐Yi
Wang, An‐Su
Sun, Ling‐Xia
Huang, Ni‐Jiao
Yang, Chang‐Wei
Cao, Yu
Bai, Tao
Lan, Yang
Liu, Sheng
Yuan, Hao
author_sort Niu, Yong‐Min
collection PubMed
description Decubitus ulcers are a common spinal cord injury (SCI) complication that puts patients' lives in danger and has emerged as a more prevalent issue in modern clinical rehabilitation and care. Decubitus ulcers in humans can currently be treated in a number of different ways, but there are fewer studies on how to treat and care for decubitus ulcers in macaques. To treat a 20‐year‐old adult male macaque monkey with SCI and decubitus ulcers after a quarter transection of the thoracic spinal cord, a number of scientific care procedures and pharmaceutical treatments, such as dietary changes and topical or intravenous administration of medication, were carried out and continuously monitored in real‐time. In comparison to the untreated group, we observed a significant improvement in decubitus wound healing in the macaques. In this article, we provide a good protocol for decubitus ulcer care after SCI and suggest that future experimental animal modeling needs to focus on issues such as care for postoperative complications.
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spelling pubmed-105289752023-10-02 A case report of the treatment and care of decubitus ulcers in macaques with spinal cord injury Niu, Yong‐Min Qin, Hao‐Yue Liu, Jin‐Xiang Li, Xin‐Yi Wang, An‐Su Sun, Ling‐Xia Huang, Ni‐Jiao Yang, Chang‐Wei Cao, Yu Bai, Tao Lan, Yang Liu, Sheng Yuan, Hao Ibrain Case Report Decubitus ulcers are a common spinal cord injury (SCI) complication that puts patients' lives in danger and has emerged as a more prevalent issue in modern clinical rehabilitation and care. Decubitus ulcers in humans can currently be treated in a number of different ways, but there are fewer studies on how to treat and care for decubitus ulcers in macaques. To treat a 20‐year‐old adult male macaque monkey with SCI and decubitus ulcers after a quarter transection of the thoracic spinal cord, a number of scientific care procedures and pharmaceutical treatments, such as dietary changes and topical or intravenous administration of medication, were carried out and continuously monitored in real‐time. In comparison to the untreated group, we observed a significant improvement in decubitus wound healing in the macaques. In this article, we provide a good protocol for decubitus ulcer care after SCI and suggest that future experimental animal modeling needs to focus on issues such as care for postoperative complications. John Wiley and Sons Inc. 2023-05-22 /pmc/articles/PMC10528975/ /pubmed/37786554 http://dx.doi.org/10.1002/ibra.12105 Text en © 2023 The Authors. Ibrain published by Affiliated Hospital of Zunyi Medical University (AHZMU) and Wiley‐VCH GmbH. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Niu, Yong‐Min
Qin, Hao‐Yue
Liu, Jin‐Xiang
Li, Xin‐Yi
Wang, An‐Su
Sun, Ling‐Xia
Huang, Ni‐Jiao
Yang, Chang‐Wei
Cao, Yu
Bai, Tao
Lan, Yang
Liu, Sheng
Yuan, Hao
A case report of the treatment and care of decubitus ulcers in macaques with spinal cord injury
title A case report of the treatment and care of decubitus ulcers in macaques with spinal cord injury
title_full A case report of the treatment and care of decubitus ulcers in macaques with spinal cord injury
title_fullStr A case report of the treatment and care of decubitus ulcers in macaques with spinal cord injury
title_full_unstemmed A case report of the treatment and care of decubitus ulcers in macaques with spinal cord injury
title_short A case report of the treatment and care of decubitus ulcers in macaques with spinal cord injury
title_sort case report of the treatment and care of decubitus ulcers in macaques with spinal cord injury
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528975/
https://www.ncbi.nlm.nih.gov/pubmed/37786554
http://dx.doi.org/10.1002/ibra.12105
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