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Brain structure analysis of different age groups of Diannan small‐ear pigs

The objective of the study is to investigate the brain development and atrophy of Diannan small‐ear pigs in different ages using magnetic resonance imaging (MRI). A total of 12 Diannan small‐ear pigs were included and divided into the young group, adult group, and middle‐and‐old age (M&O) group...

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Autores principales: Liu, Yi‐Fan, Fang, Chang‐Le, Pi, Yu, Ke, Teng‐Fei, Chu, Ji‐Xiang, Tang, Lin‐Na, Zhang, Lan‐Chun, Wanchana, Somjit, Liao, Cheng‐De
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528979/
https://www.ncbi.nlm.nih.gov/pubmed/37786734
http://dx.doi.org/10.1002/ibra.12058
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author Liu, Yi‐Fan
Fang, Chang‐Le
Pi, Yu
Ke, Teng‐Fei
Chu, Ji‐Xiang
Tang, Lin‐Na
Zhang, Lan‐Chun
Wanchana, Somjit
Liao, Cheng‐De
author_facet Liu, Yi‐Fan
Fang, Chang‐Le
Pi, Yu
Ke, Teng‐Fei
Chu, Ji‐Xiang
Tang, Lin‐Na
Zhang, Lan‐Chun
Wanchana, Somjit
Liao, Cheng‐De
author_sort Liu, Yi‐Fan
collection PubMed
description The objective of the study is to investigate the brain development and atrophy of Diannan small‐ear pigs in different ages using magnetic resonance imaging (MRI). A total of 12 Diannan small‐ear pigs were included and divided into the young group, adult group, and middle‐and‐old age (M&O) group according to their age. The brain structure of pigs was scanned using MRI, and the brain data obtained were statistically analyzed by signal conversion and image reconstruction. Compared with the young group, the signals of most brain structures in the adult group and M&O group were significantly decreased (p < 0.05). Compared with the adult group, the signal intensity of the right caudate nucleus and the right lateral ventricle in the M&O group was significantly increased, while the signal intensity of other regions was almost significantly decreased (p < 0.05). Compared with the young group, both adult and M&O groups had some degree of brain atrophy. Brain atrophy in the precuneus and the inferior temporal gyrus was more predominant in the M&O group in comparison with the adult group. The present study demonstrated that the brain signal of Diannan small‐ear pigs gradually diminished with age, while the degree of brain atrophy was the opposite, providing the basic data on the brain of Diannan small‐ear pigs.
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spelling pubmed-105289792023-10-02 Brain structure analysis of different age groups of Diannan small‐ear pigs Liu, Yi‐Fan Fang, Chang‐Le Pi, Yu Ke, Teng‐Fei Chu, Ji‐Xiang Tang, Lin‐Na Zhang, Lan‐Chun Wanchana, Somjit Liao, Cheng‐De Ibrain Original Articles The objective of the study is to investigate the brain development and atrophy of Diannan small‐ear pigs in different ages using magnetic resonance imaging (MRI). A total of 12 Diannan small‐ear pigs were included and divided into the young group, adult group, and middle‐and‐old age (M&O) group according to their age. The brain structure of pigs was scanned using MRI, and the brain data obtained were statistically analyzed by signal conversion and image reconstruction. Compared with the young group, the signals of most brain structures in the adult group and M&O group were significantly decreased (p < 0.05). Compared with the adult group, the signal intensity of the right caudate nucleus and the right lateral ventricle in the M&O group was significantly increased, while the signal intensity of other regions was almost significantly decreased (p < 0.05). Compared with the young group, both adult and M&O groups had some degree of brain atrophy. Brain atrophy in the precuneus and the inferior temporal gyrus was more predominant in the M&O group in comparison with the adult group. The present study demonstrated that the brain signal of Diannan small‐ear pigs gradually diminished with age, while the degree of brain atrophy was the opposite, providing the basic data on the brain of Diannan small‐ear pigs. John Wiley and Sons Inc. 2022-08-13 /pmc/articles/PMC10528979/ /pubmed/37786734 http://dx.doi.org/10.1002/ibra.12058 Text en © 2022 The Authors. Ibrain published by Affiliated Hospital of Zunyi Medical University (AHZMU) and Wiley‐VCH GmbH. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Liu, Yi‐Fan
Fang, Chang‐Le
Pi, Yu
Ke, Teng‐Fei
Chu, Ji‐Xiang
Tang, Lin‐Na
Zhang, Lan‐Chun
Wanchana, Somjit
Liao, Cheng‐De
Brain structure analysis of different age groups of Diannan small‐ear pigs
title Brain structure analysis of different age groups of Diannan small‐ear pigs
title_full Brain structure analysis of different age groups of Diannan small‐ear pigs
title_fullStr Brain structure analysis of different age groups of Diannan small‐ear pigs
title_full_unstemmed Brain structure analysis of different age groups of Diannan small‐ear pigs
title_short Brain structure analysis of different age groups of Diannan small‐ear pigs
title_sort brain structure analysis of different age groups of diannan small‐ear pigs
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10528979/
https://www.ncbi.nlm.nih.gov/pubmed/37786734
http://dx.doi.org/10.1002/ibra.12058
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