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Different chromatin-scanning modes lead to targeting of compacted chromatin by pioneer factors FOXA1 and SOX2
Pioneer transcription factors interact with nucleosomes to scan silent, compact chromatin, enabling cooperative events that modulate gene activity. While at a subset of sites pioneer factors access chromatin by assisted loading with other transcription factors, the nucleosome-binding properties of p...
Autores principales: | Lerner, Jonathan, Katznelson, Andrew, Zhang, Jingchao, Zaret, Kenneth S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529229/ https://www.ncbi.nlm.nih.gov/pubmed/37405916 http://dx.doi.org/10.1016/j.celrep.2023.112748 |
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