Development of Shigella conjugate vaccines targeting Shigella flexneri 2a and S. flexneri 3a using a simple platform-approach conjugation by squaric acid chemistry

There is a need for vaccines effective against shigella infection in young children in resource-limited areas. Protective immunity against shigella infection targets the O-specific polysaccharide (OSP) component of lipopolysaccharide. Inducing immune responses to polysaccharides in young children ca...

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Detalles Bibliográficos
Autores principales: Kelly, Meagan, Mandlik, Anjali, Charles, Richelle C., Verma, Smriti, Calderwood, Stephen B., Leung, Daniel T., Biswas, Rajib, Islam, Kamrul, Kamruzzaman, Mohammad, Chowdhury, Fahima, Khanam, Farhana, Vann, Willie F., Khan, Ashraful Islam, Bhuiyan, Taufiqur Rahman, Qadri, Firdausi, Vortherms, Anthony R., Kaminski, Robert, Kováč, Pavol, Xu, Peng, Ryan, Edward T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529421/
https://www.ncbi.nlm.nih.gov/pubmed/37400283
http://dx.doi.org/10.1016/j.vaccine.2023.06.052

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