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Principled estimation and evaluation of treatment effect heterogeneity: A case study application to dabigatran for patients with atrial fibrillation

OBJECTIVE: To apply the latest guidance for estimating and evaluating heterogeneous treatment effects (HTEs) in an end-to-end case study of the Long-term Anticoagulation Therapy (RE-LY) trial, and summarize the main takeaways from applying state-of-the-art metalearners and novel evaluation metrics i...

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Detalles Bibliográficos
Autores principales: Xu, Yizhe, Bechler, Katelyn, Callahan, Alison, Shah, Nigam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10529425/
https://www.ncbi.nlm.nih.gov/pubmed/37328098
http://dx.doi.org/10.1016/j.jbi.2023.104420